Total cholesterol

Biomarker13 papers4 findings

  • Human trial1
  • Humans6

Interventions

2

Corn-derived dietary fibers

downin humans1

1 study
  1. Corn-derived dietary fibers decrease total cholesterol in humans (WMD: -7.93 mg/dL).

    Reviewsupplementation in adults

    Effects of corn-derived dietary fibers on cardiometabolic risk factors: a systematic review and meta-analysis of randomized controlled trials · Diabetes research and clinical practice · 3 Oct 2026

Corn-derived dietary fibers →

Testosterone undecanoate

downin humans1

1 study
  1. Testosterone undecanoate decreases total cholesterol in humans.

    Humansadult-onset testosterone deficiencymales

    Testosterone Undecanoate Significantly Reduces Low Density Lipoprotein Cholesterol and Triglycerides in Men With Adult-Onset Testosterone Deficiency · Andrology · 25 Sep 2026

Testosterone undecanoate →

Effects

1

Dementia

mediatesin humans1

1 study
  1. Total cholesterol mediates dementia in humans (93.91% (95% CI = 68.27%∼119.55%)).

    Humansmediation analysis of statins' effect

    Statins cut Alzheimer's risk but raise other dementia risks · Journal of Alzheimer's disease reports · 1 Jan 2026

Dementia →

Associations

1

Dementia

upin humans1

1 study
  1. Total cholesterol raises the risk of dementia in humans.

    HumansIVW-MR

    Statins cut Alzheimer's risk but raise other dementia risks · Journal of Alzheimer's disease reports · 1 Jan 2026

Dementia →

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 2Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 11Oct 2026: 417
Journal of Alzheimer's Disease ReportsHumans

Statins cut Alzheimer's risk but raise other dementia risks

A Mendelian randomization analysis found total cholesterol mediated 93.91% of statins' effect on overall dementia and 84.37% on dementia in…A Mendelian randomization analysis found total cholesterol mediated 93.91% of statins' effect on overall dementia and 84.37% on dementia in Alzheimer's disease.

Alzheimer's & DementiaHumans

HDL particle sizes show contrasting links to dementia risk

In 23,790 older adults, higher small HDL levels tracked lower dementia risk (hazard ratios 0.89 to 0.91), while very large HDL tracked higher risk…In 23,790 older adults, higher small HDL levels tracked lower dementia risk (hazard ratios 0.89 to 0.91), while very large HDL tracked higher risk (1.10 to 1.14).