Bilobetin has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Nov 15, 2026: “Bilobetin eased infection-driven immune aging in mice”.
The findings reach mice, none yet in people. 1 lab.
None of its findings points the other way.
Mice: a single group. Cells, worms or flies and humans: nothing yet.
C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
1 lab
Animals1
What did studies of bilobetin find?
3
Studies of bilobetin measured 3 outcomes: hematopoietic stem cell aging and systemic immunosenescence, MAVS signaling and mitochondrial fitness.
Hematopoietic stem cell aging and systemic immunosenescence
↓downin mice1
1 study
Bilobetin decreases hematopoietic stem cell aging and systemic immunosenescence in mice (influenza A virus infection model).
“Bilobetin, a natural biflavonoid, as a potent mitochondria-targeted compound that restores mitochondrial fitness, dampens aberrant MAVS signaling, and ameliorates both HSC aging and systemic immunosenescence.”
In experiments with nonlethal influenza infection, middle-aged mice—but not young mice—were susceptible to lasting immune deterioration.In experiments with nonlethal influenza infection, middle-aged mice—but not young mice—were susceptible to lasting immune deterioration.