Alzheimer's disease
Disease32 papers3 findingsMeSH D000544
- Humans3
- Animals7
- Model organisms3
- Cells2
- In silico1
Interventions
1Apigenin
downin worms1
1 study
Apigenin
downin worms1
Apigenin protects against Alzheimer's disease in worms.
Model organismsexpressing amyloid-beta or tau
Apigenin Improves Healthspan and Protects Against Alzheimer's Disease-Associated Proteotoxicity in C. elegans · bioRxiv · 29 Sep 2026 · Preprint
Associations
2Mosaic loss of the Y chromosome
upin humans1
1 study
Mosaic loss of the Y chromosome
upin humans1
Mosaic loss of the Y chromosome raises the risk of Alzheimer's disease in humans.
Reviewmales
Mosaic Loss of the Y Chromosome: Mechanisms and Diseases · Protein & cell · 1 Oct 2026
Ubiquitin–proteasome system
downin silico1
1 study
Ubiquitin–proteasome system
downin silico1
Alzheimer's disease is associated with ubiquitin–proteasome system in silico.
In silicoin vulnerable brain regionsbrain
A multi-region transcriptomic framework reveals global and region-specific ubiquitin-proteasome system biomarkers in Alzheimer's disease · Functional & integrative genomics · 29 Sep 2026
Latest
39Pan-AMPK activator MK-8722 improves spatial memory in Alzheimer's model mice
Systemic treatment activated liver AMPK, restored plasma metabolites, and enhanced dendritic spine maturation without altering hippocampal long-term potentiation.
Journal of neurochemistry · Nicol NI et al.
Compartment-resolved brain aging reveals distinct vascular and neurodegenerative pathways
Separating white and gray matter brain age highlights early cardiometabolic risks and divergent links to amyloid and tau pathology.
Research square · Kim H et al.
Progressive behavioral and cognitive decline in Drosophila harboring AD- associated APOE4 variants
Directly converted human neuronal spheroids preserve donor age and model Alzheimer disease
The three-dimensional cell platform maintains biological aging markers while spontaneously developing hallmark pathologies of sporadic Alzheimer disease.
bioRxiv · Alsolami S et al.