Estimated glomerular filtration rate

Biomarker13 papers5 findings

  • Humans8
  • In silico1

Interventions

1

Dapagliflozin + semaglutide

upin humans1

1 study
  1. Dapagliflozin + semaglutide increases estimated glomerular filtration rate in humans.

    Humanscompared with dapagliflozin monotherapy6 months

    Dapagliflozin Alone or Combined With Semaglutide: Cardiovascular and Renal Outcomes Among Patients With Type 2 Diabetes Mellitus in a 6-Month Real-World Retrospective Cohort Study in Saudi Arabia · Journal of the ASEAN Federation of Endocrine Societies · 13 Aug 2026

Dapagliflozin + semaglutide →

Associations

4

Bone stiffness index

upin humans1

1 study
  1. Estimated glomerular filtration rate is associated with bone stiffness index in humans.

    Humansthrough serum fibroblast growth factor-21 levels

    Renal Function, Appendicular Lean Mass, and Bone Stiffness: Indirect Associations Through Fibroblast Growth Factor 21 · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2 Oct 2026

Appendicular lean mass index

upin humans1

1 study
  1. Estimated glomerular filtration rate is associated with appendicular lean mass index in humans.

    Humansthrough serum fibroblast growth factor-21 levels

    Renal Function, Appendicular Lean Mass, and Bone Stiffness: Indirect Associations Through Fibroblast Growth Factor 21 · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2 Oct 2026

False-positive plasma P-TAU217 results

downin humans1OR 0.54

1 study
  1. Estimated glomerular filtration rate is associated with false-positive plasma p-tau217 results in humans (OR 0.54/10 mL/min/1.73 m2, 95% CI 0.35-0.82).

    Humansvs true-negative resultsplasman = 706

    Plasma p-tau217 yields discordant Alzheimer results in 8.5% of adults · Neurology · 1 Oct 2026

Sarcopenia

upin humans1

1 study
  1. Estimated glomerular filtration rate is associated with sarcopenia in humans (r=0.260).

    Humansin adult chronic kidney disease patientsn = 120

    Sarcopenia among chronic kidney disease patients attending a renal clinic in Northwest Ethiopia: a cross-sectional study of prevalence, risk factors and clinical implications · BMJ open · 28 Sep 2026

Sarcopenia →

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Frontiers in EndocrinologyHumans

Underweight carries higher kidney risk than excess adiposity

Underweight was associated with an odds ratio of 1.41 for incident kidney disease compared to 1.03 for excess adiposity in adults with diabetes.Underweight was associated with an odds ratio of 1.41 for incident kidney disease compared to 1.03 for excess adiposity in adults with diabetes.

Advanced ScienceIn silico

Facial foundation model estimates clinical biomarkers

Pretrained on 10 million images, the model assessed 62 biomarkers across eight physiological systems, reaching a median Pearson's r of 0.172 across…Pretrained on 10 million images, the model assessed 62 biomarkers across eight physiological systems, reaching a median Pearson's r of 0.172 across four cohorts.

NeurologyHumans

Plasma p-tau217 yields discordant Alzheimer results in 8.5% of adults

False-negative blood results occurred in 5.6% of participants compared with false positives in 2.8%, with mismatches tied to kidney function, BMI, and…False-negative blood results occurred in 5.6% of participants compared with false positives in 2.8%, with mismatches tied to kidney function, BMI, and clinical stage.

Clinical Journal of the American Society of NephrologyHumans

Physical performance links to heart failure and death in CKD

Among 3,038 adults with chronic kidney disease, each 1-point lower physical performance score was associated with a 10% higher heart failure risk and…Among 3,038 adults with chronic kidney disease, each 1-point lower physical performance score was associated with a 10% higher heart failure risk and 15% higher mortality.