Coenzyme Q10
Intervention2 papers3 findingsPubChem 5281915ChEBI 46245MeSH C024989
- Animals1
- Cells1
Outcomes
3Cops3
upin mice1
1 study
Cops3
upin mice1
Coenzyme Q10 increases Cops3 in mice.
“Proteomic analysis identified increased COPS3 abundance in MKs from CoQ10-treated 24-month-old mice.”
Animalsmegakaryocyte12 weeksmales
Dietary CoQ10 improves megakaryocyte function and reduces platelet hyperreactivity in aging mice · Aging cell · 30 Sep 2026
Autophagy
upin mice1
1 study
Autophagy
upin mice1
Coenzyme Q10 activates autophagy in mice.
“Changes in the LC3-II/LC3-I ratio and p62 in bone marrow MKs were consistent with enhanced autophagy.”
Animalsaged micemegakaryocyte12 weeksmales
Dietary CoQ10 improves megakaryocyte function and reduces platelet hyperreactivity in aging mice · Aging cell · 30 Sep 2026
Megakaryocyte
upin mice1
1 study
Megakaryocyte
upin mice1
Coenzyme Q10 improves megakaryocyte in mice.
“CoQ10 enhanced MK proliferation, maturation, and polyploidization in aged mice.”
Animalsaged micebone marrow12 weeksmales
Dietary CoQ10 improves megakaryocyte function and reduces platelet hyperreactivity in aging mice · Aging cell · 30 Sep 2026
Latest
4Enhanced Extracellular Matrix Synthesis-Related Responses Induced by Ubiquinol-10 Derivatives in Human Dermal Fibroblasts
Dietary CoQ10 improves megakaryocyte function and reduces platelet hyperreactivity in aging mice
The supplement boosted autophagy via COPS3, enhancing megakaryocyte maturation and polyploidization without altering baseline platelet counts.
Aging cell · Xu Y et al.