Resistance training

Intervention19 papers16 findingsMeSH D055070

  • Human trial7
  • Humans1

Outcomes

15

Leg extensor performance

upin humans1

1 study
  1. Resistance training improves leg extensor performance in humans.

    Human trial12 weeksn = 27

    The effects of chronic beetroot juice supplementation with resistance training on skeletal muscle mitochondrial and redox markers in middle-aged and older adults · European journal of applied physiology · 3 Oct 2026

Mitochondrial biogenesis (PGC-1α)

upin humans1

1 study
  1. Resistance training increases mitochondrial biogenesis (PGC-1α) in humans.

    Human trialtotal body RT (2 days per week)vastus lateralis12 weeksn = 27

    The effects of chronic beetroot juice supplementation with resistance training on skeletal muscle mitochondrial and redox markers in middle-aged and older adults · European journal of applied physiology · 3 Oct 2026

Mitochondrial biogenesis (PGC-1α) →

CD11c+ macrophages

upin humans1

1 study
  1. Resistance training increases CD11c+ macrophages in humans.

    Human trialskeletal muscle6 weeks

    Resistance exercise shifts muscle progenitor cells to support growth in older adults · bioRxiv · 28 Sep 2026 · Preprint

CD11c+ macrophages →

CD90 high FAPs

upin humans1

1 study
  1. Resistance training increases CD90 high FAPs in humans.

    Human trialskeletal muscle6 weeks

    Resistance exercise shifts muscle progenitor cells to support growth in older adults · bioRxiv · 28 Sep 2026 · Preprint

CD90 high FAPs →

Transcriptomics

no changein humans1

1 study
  1. Resistance training has no effect on transcriptomics in humans.

    Human trialafter immobilization4 weeksfemalesn = 54

    Exercise mitigates disuse atrophy by building muscle reserve · medRxiv · 27 Sep 2026 · Preprint

Muscle fiber cross-sectional area

upin humans1+18%

1 study
  1. Resistance training increases muscle fiber cross-sectional area in humans (+17.7%).

    Human trialquadriceps4 weeksfemalesn = 54

    Exercise mitigates disuse atrophy by building muscle reserve · medRxiv · 27 Sep 2026 · Preprint

Maximal voluntary contraction

upin humans1+15%

1 study
  1. Resistance training increases maximal voluntary contraction in humans (+15.2%).

    Human trialquadriceps4 weeksfemalesn = 54

    Exercise mitigates disuse atrophy by building muscle reserve · medRxiv · 27 Sep 2026 · Preprint

Quadriceps cross-sectional area

upin humans1+6.7%

1 study
  1. Resistance training increases quadriceps cross-sectional area in humans (+6.7%).

    Human trialquadriceps4 weeksfemalesn = 54

    Exercise mitigates disuse atrophy by building muscle reserve · medRxiv · 27 Sep 2026 · Preprint

Appetite

no changein humans1

1 study
  1. Resistance training has no effect on appetite in humans.

    Human trial12-weeksmalesn = 33

    Appetite Responses Over 24-h Before and After 12-Weeks of Resistance Exercise in Older Male Adults: Secondary data analysis of a randomised trial · Physiology & behavior · 27 Sep 2026

Appendicular lean mass index

no changein humans1

1 study
  1. Resistance training has no effect on appendicular lean mass index in humans (0.03 kg·m -2 (95% CI: -0.09 to 0.15)).

    “appendicular lean mass index: 0.03 kg·m -2 [-0.09 to 0.15]), indicating no clear differences across groups.”

    Human trial12 weeksn = 93

    Effects of Daily Rhythm-Aligned Training on Skeletal Muscle Adaptation in Older Adults: A Randomized Controlled Trial · Journal of cachexia, sarcopenia and muscle · 26 Sep 2026

Appendicular lean mass index →

All 15

Locomotor performance

upin humans1

1 study
  1. Resistance training improves locomotor performance in humans.

    Review8 to 12 weeks

    Different Types of Training on Spatiotemporal Parameters of Gait in Older Adults: A Scoping Review · Rehabilitacion · 25 Sep 2026

Quality of life

no changein humans1

1 study
  1. Resistance training has no effect on quality of life in humans.

    Human trial3-monthn = 24

    The effectiveness of resistance training for patients with degenerative arthritis after total joint arthroplasty: a pilot randomized controlled study · BMC musculoskeletal disorders · 28 Aug 2026

Pain intensity

downin humans1

1 study
  1. Resistance training decreases pain intensity in humans.

    Human trial3-monthn = 24

    The effectiveness of resistance training for patients with degenerative arthritis after total joint arthroplasty: a pilot randomized controlled study · BMC musculoskeletal disorders · 28 Aug 2026

Dynamic balance

upin humans1

1 study
  1. Resistance training improves dynamic balance in humans.

    Human trial3-monthn = 24

    The effectiveness of resistance training for patients with degenerative arthritis after total joint arthroplasty: a pilot randomized controlled study · BMC musculoskeletal disorders · 28 Aug 2026

Lower limb muscular endurance

upin humans1

1 study
  1. Resistance training improves lower limb muscular endurance in humans.

    Human trial3-monthn = 24

    The effectiveness of resistance training for patients with degenerative arthritis after total joint arthroplasty: a pilot randomized controlled study · BMC musculoskeletal disorders · 28 Aug 2026

Associations

1

Favorable self-rated health

upin humans1

1 study
  1. Resistance training is associated with favorable self-rated health in humans.

    “muscle-strengthening PA was consistently associated with favorable SRH.”

    Humansn = 4,079

    Self-Rated Health Associated with Chronic Diseases and Types of Physical Activity Among Middle-Aged and Older Adults: A Cross-Sectional Study Using Explainable Machine Learning · Journal of clinical medicine · 13 Sep 2026

Latest

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bioRxivHuman trialPreprint

Resistance exercise shifts muscle progenitor cells to support growth in older adults

Blood flow restricted resistance training expands pro-myogenic fibro-adipogenic progenitors and inflammatory macrophages during muscle hypertrophy in…Blood flow restricted resistance training expands pro-myogenic fibro-adipogenic progenitors and inflammatory macrophages during muscle hypertrophy in older individuals.

medRxivHuman trialPreprint

Exercise mitigates disuse atrophy by building muscle reserve

In women undergoing limb immobilization, prehabilitation increased quadriceps area by 6.7% before disuse, preserving more post-immobilization muscle…In women undergoing limb immobilization, prehabilitation increased quadriceps area by 6.7% before disuse, preserving more post-immobilization muscle despite identical 3.2% relative losses.