STING1
Gene3 papers2 findingsHGNC 27962MGI 1919762NCBI Gene 340061Taxon 9606
- Humans1
- Animals1
Associations
2CD4+ T cell count
upin humans1
1 study
CD4+ T cell count
upin humans1
STING1 is associated with CD4+ T cell count in humans.
Humansin chronic PLWH on stable ART carrying R232H polymorphismn = 60
Hypomorphic STING1/TMEM173 variants may support immuno-metabolic resilience in aging people living with HIV · GeroScience · 28 Sep 2026
Dyslipidemia
downin humans1
1 study
Dyslipidemia
downin humans1
STING1 lowers the risk of dyslipidemia in humans.
Humansin chronic PLWH on stable ART carrying R71H, G230A and R293Q allelesn = 60
Hypomorphic STING1/TMEM173 variants may support immuno-metabolic resilience in aging people living with HIV · GeroScience · 28 Sep 2026
Latest
3Extracellular cGAMP drives neuroinflammation and premature aging phenotypes in mice
Loss of the cGAMP-degrading enzyme ENPP1 allows microglia-derived signaling molecules to trigger STING-dependent inflammation across multiple brain…Loss of the cGAMP-degrading enzyme ENPP1 allows microglia-derived signaling molecules to trigger STING-dependent inflammation across multiple brain cell types.