PopulationsHumans

Divergent biological consequences of APOE isoforms across industrialized and non-industrial environments

Fig 1. Conceptual model and hypothesized differences in biological relationships between non-industrial versus industrialized environments. — Fig 1. Conceptual model and hypothesized differences in biological relationships between non-industrial versus industrialized environments.Conceptual model and hypothesized differences in biological relationships between non-industrial versus industrialized environments.Watowich et al.

PLOS Genetics

The paper

Marina M. Watowich, Rachel M. Petersen, Layla Brassington,

Audrey M. Arner, Grace Rodenberg, Tan Bee Ting A P Tan Boon Huat, Kar Lye Tam, Em Schellenberg, Izandis bin Mohd Sayed, Echwa John, John C. Kahumbu, Benjamin Muhoya, Michael Gurven, Benjamin C. Trumble, Sospeter Ngoci Njeru, Dino J. Martins, Julien F. Ayroles, Yvonne Ai Lian Lim, Vivek Vasi Venkataraman, Ian J. Wallace, Thomas S. Kraft,

Vanderbilt University

PLOS Genetics · 8 Sep 2026

doi.org/10.1371/journal.pgen.1012285 PubMed 42709892

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