Microbiome composition

Pathway31 papers7 findingsMeSH D064806

  • Human trial4
  • Humans9
  • Animals3

Interventions

1

Bifidobacterium breve

no changein humans1

1 study
  1. Bifidobacterium breve has no effect on microbiome composition in humans.

    “The gut microbiota composition did not differ between groups.”

    Human trialpatients with sarcopenia2 × 10 10 cells/day24 weeks

    Effects of Heat-Killed Bifidobacterium breve B-3, a Postbiotic, on Muscle Mass-Related Parameters in Patients with Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial · Nutrients · 20 Sep 2026

Bifidobacterium breve →

Effects

1

Cognitive function

upin humans1

1 study
  1. Microbiome composition improves cognitive function in humans (MD = 1.28, 95% CI = 0.15-2.40).

    “Meta-analysis of a sub-group resulted in a statistically significant (MD = 1.28; 95% CI = 0.15-2.40; P”

    Reviewhealthy older adults and those with cognitive impairment

    Gut microbiome modulation can improve cognitive function in older adults: a systematic review and meta-analysis · Age and ageing · 1 Sep 2026

Associations

5

Cancer risk

upin humans1

1 study
  1. Microbiome composition is associated with cancer risk in humans.

    Review

    Importance of faecal sample collection in prospective cohort studies to evaluate the effect of the gut microbiome on cancer development · The Lancet. Microbe · 1 Oct 2026

Cancer risk →

NGF

mixedin reviews1

1 study
  1. Microbiome composition is associated with NGF.

    Reviewunder specific neuroimmune contexts

    The potential role and research progress of the gut microbiota-NGF axis in postmenopausal bone homeostasis imbalance · Frontiers in immunology · 16 Sep 2026

NGF →

Drug response

mixedin humans1

1 study
  1. Microbiome composition is associated with drug response in humans.

    Reviewmicrobiome remodeling

    Menopause-associated gut microbiome remodeling and pharmacomicrobiomics: emerging mechanisms influencing drug response · Frontiers in microbiomes · 15 Sep 2026

Menopause

mixedin humans1

1 study
  1. Menopause is associated with microbiome composition in humans.

    Reviewmenopause

    Menopause-associated gut microbiome remodeling and pharmacomicrobiomics: emerging mechanisms influencing drug response · Frontiers in microbiomes · 15 Sep 2026

Classifier performance

upin humans1

1 study
  1. Microbiome composition is associated with classifier performance in humans (0.76-0.99).

    “reported areas under the curve (AUCs) span 0.76-0.99 under internal validation”

    Reviewunder internal validation

    Toward AI-Driven Detection of Asymptomatic Chronic Conditions from Stool Metagenomics and Dietary Data: A Multimodal Deep Learning Framework for T1DM, T2DM, MOS/PCOS, Cancer, and Autoimmune Disease · Microorganisms · 24 Aug 2026

Latest

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bioRxivHumansPreprint

Vaginal estrogen links to premenopausal-like bladder microbes

In women, at least six weeks of vaginal estrogen was associated with higher urinary lactobacilli and fewer pathogens, partially mirroring the…In women, at least six weeks of vaginal estrogen was associated with higher urinary lactobacilli and fewer pathogens, partially mirroring the premenopausal urinary microenvironment.