Human trial50 participants24 weeksRandomised trial

Effects of Heat-Killed Bifidobacterium breve B-3, a Postbiotic, on Muscle Mass-Related Parameters in Patients with Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial

Figure 1. CONSORT flow diagram showing participant flow through the study.CONSORT flow diagram showing participant flow through the study.Asaoka et al. · CC BY

Nutrients

Abstract

Background/Objectives : Sarcopenia contributes to frailty and functional decline in older adults; however, effective adjunctive strategies remain limited.

Bifidobacterium breve
Microbiome composition
Sarcopenia
25-hydroxyvitamin D
EAT-10
Humans

The paper

Daisuke Asaoka, Shin Yoshimoto, Noriko Katsumata,

Noriyuki Iwabuchi, Naotake Yanagisawa, Toshitaka Odamaki, Jin‐zhong Xiao, Tsutomu Takeda, Shigeo Koido, Toshifumi� Ohkusa, Akihito Nagahara,

Nobuhiro Sato

Juntendo University

Nutrients · 20 Sep 2026 · CC BY

doi.org/10.3390/nu18183074 PubMed 42797058

Effects of Heat-Killed Bifidobacterium breve B-3, a Postbiotic, on Muscle Mass-Related Parameters in Patients with Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial

Abstract

The paper

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Effects of Heat-Killed Bifidobacterium breve B-3, a Postbiotic, on Muscle Mass-Related Parameters in Patients with Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial

Abstract

The paper

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