Heart failure
Disease2 papers1 findingMeSH D006333
- Humans1
Associations
1Organ age gap
upin humans1
1 study
Organ age gap
upin humans1
Organ age gap is associated with heart failure in humans.
Humansat baseline across HF severity
Proteomic multi-organ aging accelerates before adverse events in heart failure patients · European journal of heart failure · 25 Sep 2026
Latest
4Heart Failure: Lipid Metabolism Disorders Driving Cellular Senescence Through a Vicious Cycle, and Possible Intervention Strategies
ReviewFrontiers in bioscience (Landmark edition)
Persistent interferon-gamma fuels chronic cardiac remodeling after heart attacks in aged mice
A conserved interferon-gamma signature and heightened T cell recruitment drive worse long-term heart failure outcomes in older mice following myocardial infarction.
Journal of molecular and cellular cardiology · Melika ET et al.
Impaired mitochondrial proteostasis underlies cardiomyocyte bioenergetic dysfunction in a murine 3-hit model of heart failure with preserved ejection fraction
AnimalsAmerican journal of physiology. Heart and circulatory physiology
Proteomic multi-organ aging accelerates before adverse events in heart failure patients
Organ age gaps for the kidney, lung, and immune system predicted patient outcomes independently of standard clinical biomarkers.
European journal of heart failure · Qu K et al.