Cognitive dysfunction
Disease5 papersMeSH D060825
- Humans4
- Animals1
Latest
11Silencing LCN2 eases postoperative cognitive deficits in mice
AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.
Impaired glymphatic clearance links inflammation to accelerated brain aging in schizophrenia
Neuroimaging and post-mortem transcriptomics connect disrupted astrocytic aquaporin-4 polarization and blood-brain barrier breakdown to increased…Neuroimaging and post-mortem transcriptomics connect disrupted astrocytic aquaporin-4 polarization and blood-brain barrier breakdown to increased epigenetic and brain age.
Cardiometabolic multimorbidity tied to depression in older adults
Depressive symptoms occurred in 38.6% of adults with cardiometabolic multimorbidity versus 33.0% without it, yielding an adjusted hazard ratio of…Depressive symptoms occurred in 38.6% of adults with cardiometabolic multimorbidity versus 33.0% without it, yielding an adjusted hazard ratio of 1.25.
Investigation of the effect of berberine on memory and learning in aged rats undergoing sevoflurane anesthesia
Disturbed Spatial Learning and Hippocampal Molecular and Histological Alterations in Middle-Aged Rats with a History of Polycystic Ovary Syndrome
Frailty increases vulnerability to postoperative cognitive dysfunction following general anesthesia in aged rats
Dual cognitive and motor training improves cognitive function in aging rats
The combined regimen lowered TMAO accumulation and suppressed inflammatory signaling more effectively than cognitive training alone.The combined regimen lowered TMAO accumulation and suppressed inflammatory signaling more effectively than cognitive training alone.