National Institute of Dental and Craniofacial Research
OrganisationROR
Trials
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease
Phase 2Recruiting202560 people15 Dec 2025clinicaltrials.gov
Phase 2Completed202215 people15 Jun 2022clinicaltrials.gov
Phase 2Active, not recruiting20199 people27 Jun 2018clinicaltrials.gov
CollaboratorPhase 4Completed201572 people26 Sept 2013clinicaltrials.gov
CollaboratorPhase 3Active, not recruiting2013440 people9 Jul 2013clinicaltrials.gov
Phase 1/2Completed201037 people6 Sept 2010clinicaltrials.gov
CollaboratorPhase 2Completed200343 people17 Jun 2008clinicaltrials.gov
Phase 2Completed200570 people16 May 2005clinicaltrials.gov
CollaboratorPhase 3Completed20042,200 people7 Dec 2004clinicaltrials.gov
CollaboratorPhase 3Completed2003420 people6 Dec 2004clinicaltrials.gov
CollaboratorPhase 3Completed2003734 people18 Nov 2004clinicaltrials.gov
CollaboratorPhase 3Completed2002128 people5 Aug 2003clinicaltrials.gov
Phase 2Completed1999120 people28 Sept 2000clinicaltrials.gov
Phase 2Completed1999150 people19 Jan 2000clinicaltrials.gov
Phase 2Completed199840 people4 Nov 1999clinicaltrials.gov
Awards made
K99Age-Related Immunometabolic Dysregulation in Periodontitis ResolutionK99DE0366172026–202817 Sept 2026reporter.nih.gov
State University of New York at Buffalo
K99Age-Related Immunometabolic Dysregulation in Periodontitis ResolutionK99DE036617US$162k2026–202817 Sept 2026reporter.nih.gov
The intersection between aging and bacteria-induced inflammationR01DE03678917 Sept 2026reporter.nih.gov
The intersection between aging and bacteria-induced inflammationR01DE036789US$609.4k17 Sept 2026reporter.nih.gov
K08Development of an Oral Microbiome Foundation Model for Systemic Diseases AssessmentK08DE0363362026–203111 Sept 2026reporter.nih.gov
K08Development of an Oral Microbiome Foundation Model for Systemic Diseases AssessmentK08DE036336US$125.7k2026–203111 Sept 2026reporter.nih.gov
R03Defining the Oral-Gut–Bone Axis: GLP Signaling Links Periodontitis to Bone LossR03DE0364712026–20288 Sept 2026reporter.nih.gov
Indiana University Indianapolis
R03Defining the Oral-Gut–Bone Axis: GLP Signaling Links Periodontitis to Bone LossR03DE036471US$317k2026–20288 Sept 2026reporter.nih.gov
R43Integrated Multiomics Diagnostics at the Point of Care for Healthy LivingR43DE0359002026–20274 Sept 2026reporter.nih.gov
Innotech Precision Medicine, Inc
R43Integrated Multiomics Diagnostics at the Point of Care for Healthy LivingR43DE035900US$365k2026–20274 Sept 2026reporter.nih.gov
R01Bottom-Up Assembly of Functional Salivary Gland TissuesR01DE0296552026–20314 Sept 2026reporter.nih.gov
R01Bottom-Up Assembly of Functional Salivary Gland TissuesR01DE029655US$512.1k2026–20314 Sept 2026reporter.nih.gov
R03Role of CASP8 and HRAS co-mutation in oral epithelium malignant transformationR03DE0355442026–202827 Aug 2026reporter.nih.gov
State University of New York at Buffalo
R03Role of CASP8 and HRAS co-mutation in oral epithelium malignant transformationR03DE035544US$320.2k2026–202827 Aug 2026reporter.nih.gov
R56Multimodal Bioelectroceutical Strategies for Alveolar Bone Regeneration in Diabetes and AgingR56DE0361612026–202727 Aug 2026reporter.nih.gov
University of Nebraska Medical Center
R56Multimodal Bioelectroceutical Strategies for Alveolar Bone Regeneration in Diabetes and AgingR56DE036161US$383.8k2026–202727 Aug 2026reporter.nih.gov
F31Investigating the role of AP-1 during craniofacial ligament regenerationF31DE0360942026–202824 Aug 2026reporter.nih.gov
Columbia University Health Sciences
F31Investigating the role of AP-1 during craniofacial ligament regenerationF31DE036094US$50.9k2026–202824 Aug 2026reporter.nih.gov
R01Targeting P21 positive senescent cells for alleviating TMJ degenerationR01DE0330042026–202924 Aug 2026reporter.nih.gov
Medical University of South Carolina
R01Targeting P21 positive senescent cells for alleviating TMJ degenerationR01DE033004US$384.5k2026–202924 Aug 2026reporter.nih.gov