SUCNR1

Gene

1 paper1 finding

  • 1 lab in 1 country
  • Animals1

Associations

1

Diastolic dysfunction

upin mice1

1 study
  1. SUCNR1 is associated with diastolic dysfunction in mice.

    “succinate signaling through SUCNR1/GPR91 promotes PKM2 succinylation and dimerization, creating a profibrotic network associated with aging-related diastolic dysfunction.”

    AnimalsSUCNR1-/- mice

    Succinate-driven PKM2 succinylation and dimerization accelerates age-associated cardiac fibrosis

    Communications biology10 Dec 2025

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