National Institute of Neurological Disorders and Stroke

Richard J. Youle

NIH Distinguished Investigator28 Sept 2026irp.nih.gov

Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)

Phase 1Recruiting30 people3 Oct 2025clinicaltrials.gov

NCT06679374

CollaboratorPhase 2Recruiting102 people7 Nov 2024clinicaltrials.gov

NCT06008795

CollaboratorPhase 2Recruiting195 people24 Aug 2023clinicaltrials.gov

NCT05187377

CollaboratorPhase 2Completed32 people11 Jan 2022clinicaltrials.gov

NCT05074485

CollaboratorPhase 1Status unknown70 people12 Oct 2021clinicaltrials.gov

NCT05047172

CollaboratorPhase 3Active, not recruiting1,683 people17 Sept 2021clinicaltrials.gov

NCT05009992

CollaboratorPhase 2Recruiting360 people18 Aug 2021clinicaltrials.gov

NCT04643821

CollaboratorEarly phase 1Completed30 people25 Nov 2020clinicaltrials.gov

NCT04141020

CollaboratorPhase 2Recruiting80 people28 Oct 2019clinicaltrials.gov

NCT04025554

Phase 1/2Completed8 people19 Jul 2019clinicaltrials.gov

NCT03983850

CollaboratorPhase 1/2Active, not recruiting105 people12 Jun 2019clinicaltrials.gov

NCT03907046

CollaboratorPhase 3Recruiting700 people8 Apr 2019clinicaltrials.gov

NCT03589976

CollaboratorPhase 2Terminated47 people18 Jul 2018clinicaltrials.gov

NCT03456687

CollaboratorPhase 1Completed5 people7 Mar 2018clinicaltrials.gov

NCT03192215

CollaboratorPhase 3Terminated1,015 people20 Jun 2017clinicaltrials.gov

NCT03106740

CollaboratorPhase 2Completed60 people10 Apr 2017clinicaltrials.gov

NCT03104725

Phase 1Terminated6 people7 Apr 2017clinicaltrials.gov

NCT03047980

CollaboratorPhase 2/3Completed10 people9 Feb 2017clinicaltrials.gov

NCT02991807

CollaboratorPhase 1/2Completed46 people14 Dec 2016clinicaltrials.gov

NCT02595489

CollaboratorPhase 1Completed21 people3 Nov 2015clinicaltrials.gov

Carrie R Mcdonald

Lifespan Epilepsy Network Signatures (LENS): Leveraging ENIGMA-Epilepsy to Predict Cognitive Aging and Surgical OutcomesR01NS12282718 Sept 2026reporter.nih.gov

University of California, San Diego

Lifespan Epilepsy Network Signatures (LENS): Leveraging ENIGMA-Epilepsy to Predict Cognitive Aging and Surgical OutcomesR01NS122827US$672.1k18 Sept 2026reporter.nih.gov

James D Weiland

Advancing High-Density Carbon Fiber Electrode Arrays for Commercial Neurotechnology ApplicationsR44NS14591218 Sept 2026reporter.nih.gov

Florian Solzbacher

Advancing High-Density Carbon Fiber Electrode Arrays for Commercial Neurotechnology ApplicationsR44NS14591218 Sept 2026reporter.nih.gov

Charla Lindley Howard

Advancing High-Density Carbon Fiber Electrode Arrays for Commercial Neurotechnology ApplicationsR44NS14591218 Sept 2026reporter.nih.gov

Christopher Leroy Frewin

Advancing High-Density Carbon Fiber Electrode Arrays for Commercial Neurotechnology ApplicationsR44NS14591218 Sept 2026reporter.nih.gov

Spike Neuro Llc

Advancing High-Density Carbon Fiber Electrode Arrays for Commercial Neurotechnology ApplicationsR44NS145912US$1.7m18 Sept 2026reporter.nih.gov

W. Oliver Tobin

Astrocyte exosomes as senescence biomarkers and drivers of progression in multiple sclerosis patientsR01NS14652317 Sept 2026reporter.nih.gov

David Pitt

Astrocyte exosomes as senescence biomarkers and drivers of progression in multiple sclerosis patientsR01NS14652317 Sept 2026reporter.nih.gov

Yale University

Astrocyte exosomes as senescence biomarkers and drivers of progression in multiple sclerosis patientsR01NS146523US$619.3k17 Sept 2026reporter.nih.gov

Stefano Tarantini

Time-Restricted Feeding as a Therapeutic Intervention Against Acute White Matter Ischemic Injury in AgingR01NS14311217 Sept 2026reporter.nih.gov

University of Oklahoma Hlth Sciences Ctr

Time-Restricted Feeding as a Therapeutic Intervention Against Acute White Matter Ischemic Injury in AgingR01NS143112US$566.7k17 Sept 2026reporter.nih.gov

Jerry Wang

Insights from Mural Cells for Precision Medicine in Brain Arteriovenous MalformationsF31NS14778824 Aug 2026reporter.nih.gov

University of California, San Francisco

Insights from Mural Cells for Precision Medicine in Brain Arteriovenous MalformationsF31NS147788US$43.1k24 Aug 2026reporter.nih.gov

Matthew Laurence

Nuclear-cytoskeletal coupling through the giant KASH protein ANC-1 maintains neuronal mechanical integrity during agingF31NS14779614 Aug 2026reporter.nih.gov

University of California at Davis

Nuclear-cytoskeletal coupling through the giant KASH protein ANC-1 maintains neuronal mechanical integrity during agingF31NS147796US$43.5k14 Aug 2026reporter.nih.gov

EXPRESS: Normal Aging Limits Cortical Network Reorganization and Behavioral Recovery after Experimental Stroke

K08NS1178882 Oct 2026api.crossref.org

Practical considerations for characterization of the external exposome in Alzheimer's disease and related dementias cohorts

R01NS1391861 Oct 2026api.crossref.org

Clinical Factors Associated With Discordant Plasma P-Tau217 and Established Alzheimer Disease Biomarkers

UF1NS125417, U01NS1209011 Oct 2026pubmed.ncbi.nlm.nih.gov

A high intensity vs. casual speed walking intervention to reverse frailty among older adults: a cluster randomized controlled trial

U01NS11385130 Sept 2026api.crossref.org

Associations between socioeconomic position index and epigenetic aging in NHANES

K23NS15137030 Sept 2026pubmed.ncbi.nlm.nih.gov

Oxygen extraction fraction mapping between normal cognition and mild cognitive impairment in older adults using quantitative BOLD

R01NS128179, U19NS12038429 Sept 2026pubmed.ncbi.nlm.nih.gov