ER unfolded protein response
Pathway8 papers1 findingGO 0030968
- Animals1
- Cells2
Interventions
1Tardbp G376D mutation
upin human cells1
1 study
Tardbp G376D mutation
upin human cells1
Tardbp G376D mutation activates ER unfolded protein response in human cells.
“In parallel, activation of the Endoplasmic Reticulum UPR (UPR ER ) was observed, indicating a coordinated engagement of cellular stress pathways.”
Cellsdermal fibroblast
Mitochondrial Quality Control Impairment Is a Hallmark of TDP-43G376D ALS Patient-Derived Fibroblasts · Antioxidants (Basel, Switzerland) · 22 Aug 2026
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