National Institute of Diabetes and Digestive and Kidney Diseases

Comparing Different Medication Regimens to Maintaining Weight Loss Among Adults With Obesity Using GLP-1s

CollaboratorPhase 4Not yet recruiting202660 people21 Sept 2026clinicaltrials.gov

Iron Absorption in The Low Oxygen Exposure and Weight Status (LOWS) Study

CollaboratorNo phaseCompleted202516 people21 Apr 2026clinicaltrials.gov

Inherited and Environmental Risks Acting on Body Weight

CollaboratorNo phaseEnrolling by invitation2026110 people24 Feb 2026clinicaltrials.gov

Effects of Meal Macronutrients on Postprandial Lipids

Phase 2Not yet recruiting2026100 people2 Jan 2026clinicaltrials.gov

Sugary Drink Labeling Study

CollaboratorNo phaseRecruiting2026543 people19 Dec 2025clinicaltrials.gov

NCT07273838

CollaboratorPhase 2Recruiting2026130 people10 Dec 2025clinicaltrials.gov

CommunityRx-Kidney Health

CollaboratorNo phaseActive, not recruiting202623 people19 Nov 2025clinicaltrials.gov

NCT07225465

CollaboratorPhase 2Not yet recruiting2026115 people6 Nov 2025clinicaltrials.gov

Role of Alpha-to-beta Cell Communication to Adapt Insulin Secretion to Insulin Resistance.

CollaboratorPhase 1Recruiting202530 people4 Nov 2025clinicaltrials.gov

The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery

CollaboratorPhase 1Recruiting2026150 people8 Oct 2025clinicaltrials.gov

NCT07211802

CollaboratorPhase 3Not yet recruiting202652 people8 Oct 2025clinicaltrials.gov

NCT07084441

CollaboratorPhase 4Recruiting2026550 people24 Jul 2025clinicaltrials.gov

NCT07056699

CollaboratorPhase 3Recruiting202624 people9 Jul 2025clinicaltrials.gov

NCT07055282

CollaboratorEarly phase 1Recruiting202532 people8 Jul 2025clinicaltrials.gov

NCT07053319

CollaboratorPhase 1Recruiting202664 people8 Jul 2025clinicaltrials.gov

NCT07053306

CollaboratorPhase 1Recruiting202529 people8 Jul 2025clinicaltrials.gov

NCT07053293

CollaboratorEarly phase 1Recruiting202522 people8 Jul 2025clinicaltrials.gov

NCT06934655

CollaboratorPhase 3Recruiting2026150 people18 Apr 2025clinicaltrials.gov

NCT06814938

CollaboratorPhase 4Active, not recruiting2025135 people7 Feb 2025clinicaltrials.gov

Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes

CollaboratorPhase 4Recruiting202550 people26 Nov 2024clinicaltrials.gov

National Institute of Diabetes and Digestive and Kidney Diseases

Y01National Health and Nutrition Examination Survey 2009-2010, Kidney componentDK12004003-US$1.3mreporter.nih.gov

National Institute of Diabetes and Digestive and Kidney Diseases

Y01National Health and Nutrition Examination Survey 2009-2010, Kidney componentDK12004003-US$1.3mreporter.nih.gov

Rosemary Braun

RC2Interorgan Genomic Atlas for Discovery of Bioenergetic Dynamics and Mechanisms of Time-Restricted FeedingRC2DK1448202026–203117 Sept 2026reporter.nih.gov

Lisa R Beutler

RC2Interorgan Genomic Atlas for Discovery of Bioenergetic Dynamics and Mechanisms of Time-Restricted FeedingRC2DK1448202026–203117 Sept 2026reporter.nih.gov

Joseph Bass

RC2Interorgan Genomic Atlas for Discovery of Bioenergetic Dynamics and Mechanisms of Time-Restricted FeedingRC2DK1448202026–203117 Sept 2026reporter.nih.gov

Grant D Barish

RC2Interorgan Genomic Atlas for Discovery of Bioenergetic Dynamics and Mechanisms of Time-Restricted FeedingRC2DK1448202026–203117 Sept 2026reporter.nih.gov

Northwestern University

RC2Interorgan Genomic Atlas for Discovery of Bioenergetic Dynamics and Mechanisms of Time-Restricted FeedingRC2DK144820US$1.6m2026–203117 Sept 2026reporter.nih.gov

John A. Howard

R43Production in maize of low-cost heat stable forms of GLP-1 and GIP receptor agonists for treatment of diabetes and obesityR43DK1482032026–202817 Sept 2026reporter.nih.gov

Applied Biotechnology Institute

R43Production in maize of low-cost heat stable forms of GLP-1 and GIP receptor agonists for treatment of diabetes and obesityR43DK148203US$288.2k2026–202817 Sept 2026reporter.nih.gov

Richard Mauritz Bergenstal

U01Mitigating Diabetic Ketoacidosis in People with T1D and Chronic Kidney Disease on an SGLT1&2 Inhibitor: Ketosis Risk Factor Determination and Incorporation into an Enhanced Glucose Ketone ReportU01DK1433792026–202817 Sept 2026reporter.nih.gov

HealthPartners Institute

U01Mitigating Diabetic Ketoacidosis in People with T1D and Chronic Kidney Disease on an SGLT1&2 Inhibitor: Ketosis Risk Factor Determination and Incorporation into an Enhanced Glucose Ketone ReportU01DK143379US$1.5m2026–202817 Sept 2026reporter.nih.gov

Cheng-Ying Ho

R01Unveiling skin-derived SIRT1 as a therapeutic target for diabetic neuropathyR01DK1459852026–203128 Aug 2026reporter.nih.gov

Johns Hopkins University

R01Unveiling skin-derived SIRT1 as a therapeutic target for diabetic neuropathyR01DK145985US$724k2026–203128 Aug 2026reporter.nih.gov

Qi Sun

R01Ultra-processed Foods, Diet Quality, and Cardiometabolic Health: An Inter-disciplinary Trans-Atlantic Collaborative ProjectR01DK1208702019–203027 Aug 2026reporter.nih.gov

Qibin Qi

R01Ultra-processed Foods, Diet Quality, and Cardiometabolic Health: An Inter-disciplinary Trans-Atlantic Collaborative ProjectR01DK1208702019–203027 Aug 2026reporter.nih.gov

Harvard University D/b/a Harvard School of Public Health

R01Ultra-processed Foods, Diet Quality, and Cardiometabolic Health: An Inter-disciplinary Trans-Atlantic Collaborative ProjectR01DK120870US$815.7k2019–203027 Aug 2026reporter.nih.gov

Rose A Gubitosi-Klug

U01Epidemiology of Diabetes Interventions and Complications (EDIC) StudyU01DK0941572011–202727 Aug 2026reporter.nih.gov

Barbara Halina Braffett

U01Epidemiology of Diabetes Interventions and Complications (EDIC) StudyU01DK0941572011–202727 Aug 2026reporter.nih.gov

Ionut Bebu

U01Epidemiology of Diabetes Interventions and Complications (EDIC) StudyU01DK0941572011–202727 Aug 2026reporter.nih.gov

Case Western Reserve University

U01Epidemiology of Diabetes Interventions and Complications (EDIC) StudyU01DK094157US$7m2011–202727 Aug 2026reporter.nih.gov

David M. Vock

U34Cardiovascular and Renal Protection with SGLT2 Inhibition in Kidney Transplant Recipients (RENAISSANCE)U34DK1419872025–202726 Aug 2026reporter.nih.gov

TMEM174 deficiency reduces longevity by promoting phosphate-driven vascular calcification

DK1249012 Oct 2026api.crossref.org

Suspended particles for omnidirectional template sacrifice for rapid vascular patterning within engineered tissues

R01DK1285512 Oct 2026api.crossref.org

Diet Composition Modifies Cardiometabolic Phenotype Development in the 4-Vinylcyclohexene Dioxide (VCD) Ovarian Failure Model of Menopause

DK133121, DK1494441 Oct 2026api.crossref.org

Future directions of osteoanabolic therapies in osteoporosis: Integrating current anabolic agents and emerging senescence-targeted strategies

R01DK1285521 Oct 2026api.crossref.org

Plant-Based Medically Tailored Groceries From a Food Pantry and Adult Cardiometabolic Outcomes

K23DK1358221 Oct 2026pubmed.ncbi.nlm.nih.gov

Efficacy of Tailored Messages for 28-Week Exercise Sustainability in People with HIV

P30DK04852030 Sept 2026api.crossref.org

Multi-National Evaluation of Low-Density Lipoprotein Cholesterol Equations in Young Adulthood for Long-Term Risk of Atherosclerotic Cardiovascular Disease

R01DK072124, R21DK08536330 Sept 2026pubmed.ncbi.nlm.nih.gov

Accelerated Biological Aging in Cholestatic Liver Disease: Telomere Attrition and Association With Disease Severity

RC2DK118619, R01DK12669129 Sept 2026api.crossref.org

Prevalence and significance of family history of kidney disease in the electronic health record in three United States health systems

R01DK11553428 Sept 2026api.crossref.org

Reversing liver sinusoidal endothelial aging restores clearance of amyloid-beta and LDL

R01DK10058026 Sept 2026api.crossref.org

A cross-species single-cell kidney epigenome atlas reveals epithelial-dominant aging-like states in disease

U54DK13430124 Sept 2026api.crossref.org

Impaired mitochondrial proteostasis underlies cardiomyocyte bioenergetic dysfunction in a murine 3-hit model of heart failure with preserved ejection fraction

R00DK113280, R01DK12141119 Sept 2026api.crossref.org

Considering microRNAs as measures of extrinsic domains of risk in the context of underlying genetic characteristics: type 2 diabetes as an exemplar

R01DK124228, X01DK115999, K26DK13728618 Sept 2026api.crossref.org

Clinical Translation of Fisetin for Age-Related Diseases: Current Evidence and Future Opportunities

R01DK13446814 Sept 2026api.crossref.org

AZGP1 deficiency promotes chronic kidney fibrosis in aging mice

U54DK13006515 Aug 2026pubmed.ncbi.nlm.nih.gov

Neighborhood Disadvantage and Dementia Risk Among Older Patients With Kidney Failure: Differences by Race/Ethnicity and Urbanicity

K01DK13942020 Jul 2026api.crossref.org

Glucosuria as a Marker of Adherence to Sodium-Glucose Cotransporter 2 Inhibitors and Clinical Outcomes in Real-World Practice

Journal of the American Society of Nephrology : JASN17 Sept 2026

Building and regenerating intestines by manipulating intestinal stem cells

Nature reviews. Gastroenterology & hepatology4 Sept 2026

Machine learning models for predicting new-onset diabetes following acute pancreatitis using real-world data

BMJ public health3 Sept 2026

Progressive Failure of Brown Adipose Tissue Remodeling Drives Metabolic Aging

ADA Scientific Sessions 2026 abstract6 Jun 2026