Proteostasis
Pathway1 paper
- Cells1
Latest
21InflammopharmacologyReview
The immunoproteasome in Alzheimer's disease: a dual regulator of tau pathology and microglial senescence
bioRxivHumansPreprint
Human neurons accumulate far more mutations over lifespan than shorter-lived mammals
Cortical neurons gain mutations at similar yearly rates across six species, leaving aged humans with uniquely high mutational burdens and…Cortical neurons gain mutations at similar yearly rates across six species, leaving aged humans with uniquely high mutational burdens and transcriptomic dysregulation.
The Journal of Pharmacy and PharmacologyReview
Traditional Chinese medicine-derived natural products and formulations as pharmacological modulators of ageing-related pathways: mechanisms and therapeutic potential
Philosophical Transactions of the Royal Society of London, Series BReview
Proteostasis and ageing dissidence
Frontiers in Molecular NeuroscienceReview
Mitohormesis linking metabolic dysfunction and neurodegeneration: implications for dementia and therapeutic strategies
Essays in BiochemistryReview
Complementary fish models for brain ageing: insights from killifish and zebrafish
GeneticsModel organisms
Krüppel-like factors modulate SKN-1 activity and lipid balance to control worm lifespan
KLF-1 drives SKN-1 activation through lipophagy-linked pathways to promote oxidative stress resistance and extend lifespan in germline-deficient…KLF-1 drives SKN-1 activation through lipophagy-linked pathways to promote oxidative stress resistance and extend lifespan in germline-deficient Caenorhabditis elegans.