Insulin sensitivity
Biomarker2 papers1 finding
- Humans1
- In silico1
Associations
1Proteomic BMI score
downin humans1
1 study
Proteomic BMI score
downin humans1
Proteomic BMI score is associated with insulin sensitivity in humans.
Humansin individuals with high predicted proteomic BMI and low measured BMI
Proteomic signatures of BMI generalize across ancestries and reveal cardiometabolic heterogeneity beyond measured BMI · medRxiv · 10 Sep 2026 · Preprint
Funding
National Institute of Diabetes and Digestive and Kidney DiseasesUS$861.8kNational Heart, Lung, and Blood InstituteUS$861.5k3 grants since 2023
National Heart, Lung, and Blood InstituteColorado State UniversityUS$197.3k2024–2029
National Institute of Diabetes and Digestive and Kidney DiseasesMassachusetts General HospitalUS$719.5k2023–2029
Mechanisms of Resistance Exercise Training for Improved Muscle Insulin Sensitivity
National Institute of Diabetes and Digestive and Kidney DiseasesMayo Clinic RochesterUS$142.4k2025–2029
Latest
111Weight Loss or Muscle Loss? Cellular Mechanisms and Clinical Strategies for Preserving Lean Mass During GLP-1-Based Therapy
Antibody reduced fat while preserving lean mass in mice
Experiments in middle-aged and aged mice found that an antibody targeting a stress-hormone signal reduced fat mass without reducing lean mass.Experiments in middle-aged and aged mice found that an antibody targeting a stress-hormone signal reduced fat mass without reducing lean mass.
Aged mice had high levels of a hormone that raises blood sugar
Experiments found increased release of the hormone in aged mice with normal or reduced responses to insulin, which lowers blood sugar.Experiments found increased release of the hormone in aged mice with normal or reduced responses to insulin, which lowers blood sugar.
Baseline Plasma Metabolites Associated with Subsequent Response to Lifestyle Intervention in People with Prediabetes
Real-world effectiveness of 6-month tirzepatide therapy on body weight and composition in adults with overweight and obesity
Mild caloric restriction accelerates atherosclerosis in mice
In ApoE-deficient mice fed for six months, mild food restriction reduced weight gain by 5% but increased circulating cholesterol and accelerated…In ApoE-deficient mice fed for six months, mild food restriction reduced weight gain by 5% but increased circulating cholesterol and accelerated plaque formation.