Cellular homeostasis
Pathway11 papers1 findingGO 0019725
- Humans3
- Animals4
- Model organisms2
Associations
1Autophagy
upin H. vulgaris1
1 study
Autophagy
upin H. vulgaris1
Autophagy is associated with cellular homeostasis in H. vulgaris.
“sustained telomerase activity, autophagy regulation, and microbiome stability in H. vulgaris are associated with stem cell renewal and long-term tissue homeostasis”
Reviewin H. vulgaris
Conditional Senescence and Longevity Mechanisms in Early-Branching Metazoans: Insights from Hydra · Current issues in molecular biology · 19 Sep 2026
Latest
14Loss of MYO1C causes age-dependent rod dysfunction in mice
Global and rod-specific knockout mice developed rhodopsin mislocalization and progressive scotopic vision loss starting at six months of age.Global and rod-specific knockout mice developed rhodopsin mislocalization and progressive scotopic vision loss starting at six months of age.
Tamoxifen causes temporary ovarian disruption without altering long-term mouse aging trajectories
A new preprint shows tamoxifen-inducible mouse models remain valid for ovarian aging research despite transient disruptions to estrous cycling.A new preprint shows tamoxifen-inducible mouse models remain valid for ovarian aging research despite transient disruptions to estrous cycling.
Aging mouse brains accumulate myelin lipids that drive lysosomal dysfunction
Lysosomal multi-omics shows altered sphingolipid breakdown leads to glycosphingolipid buildup and lysosome enlargement, especially in aging microglia.Lysosomal multi-omics shows altered sphingolipid breakdown leads to glycosphingolipid buildup and lysosome enlargement, especially in aging microglia.
Human neurons accumulate far more mutations over lifespan than shorter-lived mammals
Cortical neurons gain mutations at similar yearly rates across six species, leaving aged humans with uniquely high mutational burdens and…Cortical neurons gain mutations at similar yearly rates across six species, leaving aged humans with uniquely high mutational burdens and transcriptomic dysregulation.
Aging impairs blastema formation and tissue regeneration in Cladonema jellyfish
Older jellyfish medusae exhibit cell loss, heightened DNA damage, and defective wound closure that limit complex tentacle regrowth.Older jellyfish medusae exhibit cell loss, heightened DNA damage, and defective wound closure that limit complex tentacle regrowth.
Proteomic organ clocks predict mortality but trail established physiological and epigenetic biomarkers
In an older Scottish cohort, epigenetic age and brain volume outmatched plasma proteomic organ clocks for predicting long-term all-cause mortality.In an older Scottish cohort, epigenetic age and brain volume outmatched plasma proteomic organ clocks for predicting long-term all-cause mortality.
Impaired glymphatic clearance links inflammation to accelerated brain aging in schizophrenia
Neuroimaging and post-mortem transcriptomics connect disrupted astrocytic aquaporin-4 polarization and blood-brain barrier breakdown to increased…Neuroimaging and post-mortem transcriptomics connect disrupted astrocytic aquaporin-4 polarization and blood-brain barrier breakdown to increased epigenetic and brain age.