5 papers1 finding
Spermidine
downin rats1
Spermidine decreases skeletal muscle atrophy in rats.
“Spermidine coupled with exercise could attenuate D-gal-induced aging-related atrophy of skeletal muscle”
AnimalsD-gal-induced agingskeletal muscle42 days
Oncotarget14 Mar 2017
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUS$1.3mNational Institute on AgingUS$322.4k
Using the gut microbiome to treat skeletal muscle atrophy
National Institute of Arthritis and Musculoskeletal and Skin DiseasesUniversity of KentuckyUS$421.7k2025–2030
MuRF1 substrates and mechanisms of skeletal muscle atrophy
National Institute of Arthritis and Musculoskeletal and Skin DiseasesOklahoma Medical Research FoundationUS$181.9k2024–2026
National Institute on AgingRidgeline TherapeuticsUS$322.4k2023–2025
Experiments with lab-grown liver and muscle cells linked statin exposure to lower levels of insulin-like growth factor-1, a growth signal.Experiments with lab-grown liver and muscle cells linked statin exposure to lower levels of insulin-like growth factor-1, a growth signal.
Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.Experiments in mice with impaired DNA repair identified a female-specific metabolic pathway; a dietary supplement restored muscle force and metabolic profiles in females.
Structural analyses of humans and mice reveal that fibers shrink primarily by shedding myofibrils rather than reducing myofibril size.Structural analyses of humans and mice reveal that fibers shrink primarily by shedding myofibrils rather than reducing myofibril size.