SIRT3
Gene3 papers1 findingHGNC 14931MGI 1927665NCBI Gene 23410Taxon 9606
- Animals3
Interventions
1Inotodiol
upin mouse cells1
1 study
Inotodiol
upin mouse cells1
Inotodiol increases SIRT3 in mouse cells.
Cells
Inotodiol preserves muscle mass and function in aged mice · Signal transduction and targeted therapy · 25 Sep 2026
Latest
3Astragaloside IV reduces cardiac aging in mice by restoring mitochondrial balance
The compound lowered senescence markers and improved heart function through SIRT3-driven DRP1 deacetylation in aged mice and cultured cardiomyocytes.The compound lowered senescence markers and improved heart function through SIRT3-driven DRP1 deacetylation in aged mice and cultured cardiomyocytes.
Hallmarks of Aging Associate with High Intensity Interval Training Benefits and Frailty in Female C57Bl/6J Mice
Inotodiol preserves muscle mass and function in aged mice
The mycosterol restores mitochondrial metabolism by activating the LXRbeta-SIRT3-PGC-1alpha pathway to counter age-related muscle decline.The mycosterol restores mitochondrial metabolism by activating the LXRbeta-SIRT3-PGC-1alpha pathway to counter age-related muscle decline.