UCP2

Gene3 papers3 findings

Humans1
Animals1
Cells1

Interventions

1

Pyrroloquinoline quinone

downin animals1Very low certainty

1 study

Pyrroloquinoline quinone decreases UCP2.
Animalshippocampus
Pyrroloquinoline Quinone Improves Cognitive-Related Behavioral Performance Associated with Enhanced Mitochondrial Bioenergetics in Naturally Aged Mice · Antioxidants (Basel, Switzerland) · 24 Jul 2026

Pyrroloquinoline quinone →

Associations

1

Cardiometabolic disease risk

downin humans1upin humans1

1 study

UCP2 lowers the risk of cardiometabolic disease risk in humans.
Humansminor allele of UCP2 c.-866G > A with wild allele of UCP2 p.Ala55Val
Cardiometabolic disease risk: the joint role of the UCP1, UCP2, UCP3, and FTO gene variants · Biochimie · 3 Sep 2026
UCP2 raises the risk of cardiometabolic disease risk in humans.
Humansminor alleles of UCP2 c.-866G > A and UCP3 c.-55C > T
Cardiometabolic disease risk: the joint role of the UCP1, UCP2, UCP3, and FTO gene variants · Biochimie · 3 Sep 2026

Latest

3

BiochimieHumans3 Sep

Cardiometabolic disease risk: the joint role of the UCP1, UCP2, UCP3, and FTO gene variants

Cardiometabolic disease

Biochimica et Biophysica Acta BioenergeticsCells3 Sep

Effects of increases in temperature and genipin on mitochondrial function in primary fibroblast cells of dogs of different sizes and ages

Oxidative phosphorylation

AntioxidantsAnimals27 Aug

Pyrroloquinoline Quinone Improves Cognitive-Related Behavioral Performance Associated with Enhanced Mitochondrial Bioenergetics in Naturally Aged Mice