Nicotinamide riboside
InterventionNAD+ precursors1 paper5 findingsPubChem 439924ChEBI 15927
- Animals1
Outcomes
5Trypanosoma cruzi infection
downin mice1Very low certainty
1 study
Trypanosoma cruzi infection
downin mice1Very low certainty
Nicotinamide riboside decreases Trypanosoma cruzi infection in mice.
Animalsskeletal muscle parasite burden in acute infectionskeletal muscle
Nicotinamide riboside improves parasite control in mice · bioRxiv · 4 Oct 2026 · Preprint
Parasitemia
downin mice1Very low certainty
1 study
Parasitemia
downin mice1Very low certainty
Nicotinamide riboside decreases parasitemia in mice.
Animalsduring acute T. cruzi infection
Nicotinamide riboside improves parasite control in mice · bioRxiv · 4 Oct 2026 · Preprint
NAD+
upin mice1Very low certainty
1 study
NAD+
upin mice1Very low certainty
Nicotinamide riboside increases NAD+ in mice.
Animalsin vivo during acute T. cruzi infectionCD8-positive T cell
Nicotinamide riboside improves parasite control in mice · bioRxiv · 4 Oct 2026 · Preprint
CD38
downin mice1Very low certainty
1 study
CD38
downin mice1Very low certainty
Nicotinamide riboside decreases CD38 in mice.
Animalsin T. cruzi infectionCD8-positive T cell
Nicotinamide riboside improves parasite control in mice · bioRxiv · 4 Oct 2026 · Preprint
Mitochondrial reactive oxygen species
downin mice1Very low certainty
1 study
Mitochondrial reactive oxygen species
downin mice1Very low certainty
Nicotinamide riboside decreases mitochondrial reactive oxygen species in mice.
Animalsin T. cruzi-infected miceCD8-positive T cell
Nicotinamide riboside improves parasite control in mice · bioRxiv · 4 Oct 2026 · Preprint
Latest
1Nicotinamide riboside improves parasite control in mice
In mice infected with Trypanosoma cruzi, treatment with the NAD+ precursor improved CD8+ T-cell function and reduced parasite burden in blood and…In mice infected with Trypanosoma cruzi, treatment with the NAD+ precursor improved CD8+ T-cell function and reduced parasite burden in blood and skeletal muscle.