Down syndrome
Disease2 papersMeSH D004314
- Humans2
Latest
86Sleep Disturbances and Sarcopenia in Older Adults: Clinical Associations, Potential Mechanisms, and Management Strategies
Mediterranean Diet, Physical Activity, and Metabolic Syndrome in Breast Cancer Survivors on Adjuvant Endocrine Therapy: A Cross-Sectional Study From North Africa
Electronic frailty index predicts CAR-T outcomes in older adults
Very frail older patients had worse overall survival (HR=1.64) and event-free survival (HR=2.02) after CAR-T therapy than robust or prefrail peers.Very frail older patients had worse overall survival (HR=1.64) and event-free survival (HR=2.02) after CAR-T therapy than robust or prefrail peers.
Dietary flavonoids link to lower mortality across CKM stages
Top-quartile flavonoid intake lowered odds of stage 2 CKM syndrome to an odds ratio of 0.53 versus stage 0 among 10,754 US adults.Top-quartile flavonoid intake lowered odds of stage 2 CKM syndrome to an odds ratio of 0.53 versus stage 0 among 10,754 US adults.
Plasma pTau217 and recall test refine prognosis in Down syndrome
Using Alzheimer Biomarker Consortium-Down Syndrome data, researchers found combining plasma pTau217 with a cued recall task identifies cognitively…Using Alzheimer Biomarker Consortium-Down Syndrome data, researchers found combining plasma pTau217 with a cued recall task identifies cognitively stable adults facing clinical impairment within seven years.
H-FABP links to heart risks mostly when omega-3s are low
Highest versus lowest H-FABP tertiles had an MI hazard ratio of 2.23 in people with low omega-3s, but 1.11 in those with high levels.Highest versus lowest H-FABP tertiles had an MI hazard ratio of 2.23 in people with low omega-3s, but 1.11 in those with high levels.
Advanced CKM syndrome is linked to higher suicide risk
In over 4.6 million Korean adults followed for 10.11 years, stage 3 and 4 CKM syndrome carried hazard ratios of 1.328 and 1.319 for suicidal death.In over 4.6 million Korean adults followed for 10.11 years, stage 3 and 4 CKM syndrome carried hazard ratios of 1.328 and 1.319 for suicidal death.
Sarcopenia with metabolic syndrome links to cognitive decline
Their co-occurrence showed a 2.64-fold higher odds of persistently low cognition and 2.38-fold higher odds of rapid decline in 5,985 older adults.Their co-occurrence showed a 2.64-fold higher odds of persistently low cognition and 2.38-fold higher odds of rapid decline in 5,985 older adults.
TyG-waist index predicts cardiovascular events in older adults
In 4,169 older adults followed for six years, each standard-deviation rise in baseline TyG-waist circumference shortened time to cardiovascular events…In 4,169 older adults followed for six years, each standard-deviation rise in baseline TyG-waist circumference shortened time to cardiovascular events by 5.5%.