Oxidative phosphorylation
Pathway24 papers2 findingsGO 0006119
- Animals6
- Model organisms3
- Cells5
Interventions
2SCAF1 knockdown
upin human cells1
1 study
SCAF1 knockdown
upin human cells1
SCAF1 knockdown increases oxidative phosphorylation in human cells.
Cells
Peroxisomal stress drives cellular senescence by relocating SCAF1 to mitochondria · bioRxiv : the preprint server for biology · 23 Sep 2026 · Preprint
Hypomagnetic field
upin flies1
1 study
Hypomagnetic field
upin flies1
Hypomagnetic field activates oxidative phosphorylation in flies.
Model organisms5 nT
Hypomagnetic fields modulate lifespan, physical ability and mitochondrial metabolism in a Pink1 model of neurodegeneration · Aging · 23 Sep 2026
Latest
25Suppressing neuronal dENL/AF9 shifts metabolic and energetic profiles in aged flies
Multi-omics profiling in Drosophila links chromatin regulation to increased ATP, higher NAD-to-NADH ratios, and altered lipid metabolism in aged heads.
bioRxiv · Yeewa R et al.
Microglial depletion triggers distinct molecular responses in male and female aged mouse brains
Aged male mice showed far larger proteomic shifts than females following microglial removal, including alterations in synaptic and mitochondrial proteins.
bioRxiv : the preprint server for biology · Beganovic A et al.
Peroxisomal stress drives cellular senescence by relocating SCAF1 to mitochondria
Processed SCAF1 halts mitochondrial ribosome assembly and induces senescence in human cell models following peroxisome import stress.
bioRxiv : the preprint server for biology · Correia J et al.
Biomimetic nanozymes reduce neuroinflammation and cognitive decline in aged mice
Neutrophil-coated nanoparticles crossed the blood-brain barrier, altered microglial metabolism, and improved cognitive performance after surgery in older mice.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · Huang L et al.
Engineered exosome-mimetic nanoparticles improve liver function in aged mice
The synthetic particles deliver microRNAs and proteins to reduce senescence, lower fibrosis, and shift macrophages toward a pro-resolving state.
Biomaterials advances · Zhang L et al.