Telomere length

Biomarker11 papers7 findings

Human studies associate telomere length with Parkinson's disease, multiple system atrophy, diabetes, and drug-induced liver injury, whilst reviews link it to lithium. In female mice, high-intensity interval training increases hepatic telomere length.

Humans5
Animals1
Model organisms1

Interventions

High-intensity interval training

upin mice1

1 study

High-intensity interval training increases telomere length in mice.
Animalsshort session (≤10 minute)liver10-minute HIIT regimen 3-days-a-week8 weeksfemales
Hallmarks of Aging Associate with High Intensity Interval Training Benefits and Frailty in Female C57Bl/6J Mice · The journals of gerontology. Series A, Biological sciences and medical sciences · 25 Sep 2026

High-intensity interval training →

Associations

Socioeconomic position

no changein humans1

1 study

Socioeconomic position is associated with telomere length in humans (β = 0.04 [-0.01, 0.09]).
HumansCI contained the nullleukocyte
Associations between socioeconomic position index and epigenetic aging in NHANES · GeroScience · 30 Sep 2026

Socioeconomic position →

Multiple system atrophy

downin humans1

1 study

Multiple system atrophy is associated with telomere length in humans.
Humansblood
Preliminary insights into whole-blood mitochondrial DNA copy number and telomere length in Parkinson's disease and multiple system atrophy · Journal of neurology · 29 Sep 2026

Multiple system atrophy →

Parkinson's disease

downin humans1

1 study

Parkinson's disease is associated with telomere length in humans.
Humansblood
Preliminary insights into whole-blood mitochondrial DNA copy number and telomere length in Parkinson's disease and multiple system atrophy · Journal of neurology · 29 Sep 2026

Parkinson's disease →

Lithium

upin humans1

1 study

Lithium is associated with telomere length in humans.
“Clinical findings further suggest that chronic lithium treatment may be associated with preserved telomere length and attenuated biological brain aging in BD.”
Reviewin BDchronic
Lithium as a Potential Senostatic Agent in Central Nervous System Aging and Bipolar Disorder · Pharmaceuticals (Basel, Switzerland) · 31 Aug 2026

Lithium →

Drug-induced liver injury

downin humans1

1 study

Telomere length is associated with drug-induced liver injury in humans.
Humansin tuberculosis patientsperipheral blood mononuclear celln = 64
Telomere Length Profile and Associated Clinical Factors among Tuberculosis Patients in Indonesia · International journal of mycobacteriology · 1 Jul 2026

Drug-induced liver injury →

Diabetes mellitus

downin humans1

1 study

Telomere length is associated with diabetes mellitus in humans.
Humansin tuberculosis patientsperipheral blood mononuclear celln = 64
Telomere Length Profile and Associated Clinical Factors among Tuberculosis Patients in Indonesia · International journal of mycobacteriology · 1 Jul 2026

Diabetes mellitus →

Latest

HumansPeer-reviewedAging clocksYesterday

Proteomic organ clocks predict mortality but trail established physiological and epigenetic biomarkers

In an older Scottish cohort, epigenetic age and brain volume outmatched plasma proteomic organ clocks for predicting long-term all-cause mortality.

Aging cell · Pyrgioti M et al.

Paper

Telomere Length Profile and Associated Clinical Factors among Tuberculosis Patients in Indonesia

HumansInternational journal of mycobacteriologyYesterday

Associations between socioeconomic position index and epigenetic aging in NHANES

HumansGeroScience1 Oct

Sonnerachromones A–C from Sonneratia Apetala Delay Aging and Extend Lifespan in Caenorhabditis elegans Associated with Modulation of Telomere–Telomerase-Related Pathways

Model organismsPreprintPreprints.org30 Sep

Telomeres in Aging: Links to Clonal Hematopoiesis, Cardiovascular Disease, and Cancer

ReviewThe American journal of medicine30 Sep

HumansPeer-reviewedAging clocks30 Sep

Older adults with preserved cognition show slower biological aging and longer telomeres

An observational study in Chile linked perfect Mini-Mental State Examination scores in people over 80 to slower epigenetic clocks and longer estimated telomeres.

Aging and disease · Salech F et al.

Paper