Air pollution

Intervention6 papers5 findingsMeSH D000397

  • Humans4
  • In silico1

Outcomes

2

Ischemic stroke

no changein humans1

1 study
  1. Air pollution has no effect on ischemic stroke in humans.

    “In contrast, no significant associations were observed between air pollution metrics and ischemic stroke.”

    Humans17.6 years

    Long-term PM2.5 exposure and incident heart failure in the UK Biobank: relative and absolute risk estimates · Frontiers in public health · 14 Sep 2026

Ischemic stroke →

Bone mineral density

downin humans1

1 study
  1. Air pollution decreases bone mineral density in humans.

    “Air contaminants showed the most consistent associations with reduced bone mineral density (BMD) and osteoporosis”

    Review

    Environmental Contaminants and Osteoporosis-Related Outcomes: A Systematic Review and Meta-Analysis · Toxics · 7 Sep 2026

Associations

3

Chronic disease

upin humans1

1 study
  1. Air pollution raises the risk of chronic disease in humans.

    Reviewn = 48,645

    Proteomics reveals how air pollutants drive chronic disease · Redox biology · 23 Sep 2026

Chronic disease →

Mortality

upin humans1

1 study
  1. Air pollution raises the risk of mortality in humans.

    Reviewn = 48,645

    Proteomics reveals how air pollutants drive chronic disease · Redox biology · 23 Sep 2026

Cardiovascular disease

upin humans1HR 1.09

1 study
  1. Air pollution raises the risk of cardiovascular disease in humans (HR = 1.09, 95% CI: 1.03-1.16).

    “long-term exposure to PM 2.5 (HR = 1.09, 95% CI: 1.03-1.16) and PM 10 (HR = 1.07, 95% CI: 1.04-1.10) was significantly associated with an elevated risk of incident CVD”

    Humansfollowed through 2020n = 8,792

    Long-Term Air Pollution Exposure, Cardiovascular Disease, and Cardiometabolic Risk Factors in Middle-Aged and Older Chinese Adults: A Prospective Cohort Study · Bioengineering (Basel, Switzerland) · 23 Aug 2026

Cardiovascular disease →

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Redox BiologyHumans

Proteomics reveals how air pollutants drive chronic disease

In 48,645 UK Biobank participants, plasma proteomic profiles showed shared immune pathways and pollutant-specific mechanisms linking air pollution to…In 48,645 UK Biobank participants, plasma proteomic profiles showed shared immune pathways and pollutant-specific mechanisms linking air pollution to mortality and chronic disease risks.

NeuroepidemiologyHumans

Air pollution links to stroke risk in two population cohorts

In UK Biobank, every 5 µg/m³ increment in PM2.5 carried an incident ischemic stroke hazard ratio of 1.29, reaching 1.44 alongside high genetic…In UK Biobank, every 5 µg/m³ increment in PM2.5 carried an incident ischemic stroke hazard ratio of 1.29, reaching 1.44 alongside high genetic susceptibility.