POT1

Gene2 papers2 findings

Humans1

Effects

1

Telomere length

upin humans1

1 study

POT1 increases telomere length in humans.
Humansp.(Ile78Thr) variant
Germline POT1 variants are associated with long telomeres and an unexpected broad spectrum of malignancies · Genetics in medicine open · 5 Jul 2026

Telomere length →

Associations

1

Malignancy

upin humans1+61%

1 study

POT1 raises the risk of malignancy in humans (61%).
Humanspathogenic or likely pathogenic POT1 variants
Germline POT1 variants are associated with long telomeres and an unexpected broad spectrum of malignancies · Genetics in medicine open · 5 Jul 2026

Latest

2

Genetics in Medicine OpenHumans27 Aug

Germline POT1 variants are associated with long telomeres and an unexpected broad spectrum of malignancies

Zhongguo Fei Ai Za ZhiReview24 Aug

[China Wumeng Mountain Lung Cancer: Evidence Chain, Clinical and Molecular Characteristics of Regional Lung Cancer Related to Coal Pollution in the Yunnan-Guizhou Plateau]