Telomere

Cell component12 papersMeSH D016615GO 0000781

  • Humans7
  • Animals1
  • Model organisms1

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Alimentary Pharmacology & TherapeuticsHumans

Telomere attrition marks disease severity in chronic cholestatic liver diseases

Epigenetic telomere length analysis in patients with sclerosing or biliary cholangitis reveals converging markers of accelerated biological aging.Epigenetic telomere length analysis in patients with sclerosing or biliary cholangitis reveals converging markers of accelerated biological aging.

GenesHumans

Blood methylation clocks capture two distinct biological domains of aging

Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors…Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle exposures.