Spinal stenosis, spondylosis, disc degeneration, spondylolisthesis, or disc prolapse

Disease

1 paper1 finding

  • Humans1

Upstream

1

Telomere length

no changein humans1

1 study
  1. Telomere length has no effect on spinal stenosis, spondylosis, disc degeneration, spondylolisthesis, or disc prolapse in humans.

    “We found no evidence that genetically proxied TL was associated with spinal stenosis, spondylosis, disc degeneration, spondylolisthesis, or disc prolapse (all p>0.32).”

    HumansGenetically proxied telomere length in two-sample Mendelian randomizationleukocyte

    Longer telomeres linked to lower spine disease risk

    World neurosurgery12 Oct 2026

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World Neurosurgery

Longer telomeres linked to lower spine disease risk

In 265,805 people, longer telomeres were linked to lower rates of new spine diagnoses; the hazard ratio, comparing rates over time, was 0.953.In 265,805 people, longer telomeres were linked to lower rates of new spine diagnoses; the hazard ratio, comparing rates over time, was 0.953.

Mendelian randomisation in 265,805 peoplePopulations