ALT-007
- 1 lab in 1 country
- Funders: École Polytechnique Fédérale de Lausanne and 7 more
- Animals1
Outcomes
3Proteostasis
upin mice1upin worms1
1 study
Proteostasis
upin mice1upin worms1
ALT-007 improves proteostasis in mice.
“Mechanistic studies revealed that ALT-007 enhances protein homeostasis in Caenorhabditis elegans and mouse models of aging and age-related diseases”
Animalsmodels of aging and age-related diseases
ACS pharmacology & translational science29 Dec 2024
ALT-007 improves proteostasis in worms.
“Mechanistic studies revealed that ALT-007 enhances protein homeostasis in Caenorhabditis elegans and mouse models of aging and age-related diseases”
Model organismsmodels of aging and age-related diseases
ACS pharmacology & translational science29 Dec 2024
Muscle function
upin mice1
1 study
Muscle function
upin mice1
ALT-007 improves muscle function in mice.
“In a mouse model of age-related sarcopenia, ALT-007, administered through the diet, effectively restored muscle mass and function compromised by aging.”
Animalsmouse model of age-related sarcopeniaskeletal muscle
ACS pharmacology & translational science29 Dec 2024
Muscle mass
upin mice1
1 study
Muscle mass
upin mice1
ALT-007 increases muscle mass in mice.
“In a mouse model of age-related sarcopenia, ALT-007, administered through the diet, effectively restored muscle mass and function compromised by aging.”
Animalsmouse model of age-related sarcopeniaskeletal muscle
ACS pharmacology & translational science29 Dec 2024
Latest
ACS Pharmacology & Translational Science
Safe and Orally Bioavailable Inhibitor of Serine Palmitoyltransferase Improves Age-Related Sarcopenia
Experiments in miceMuscle