Neurodegenerative disease
Disease8 papers
- Model organisms1
Latest
37CellsPreprint
Rank normalization resolves distinct proteome degradation pathways in cultured cells
A percentile-based normalization method reveals substrate preferences between proteasomal and lysosomal clearance systems in cultured cells.
bioRxiv · Gao Z et al.
Human neurons accumulate far more mutations over lifespan than shorter-lived mammals
Cortical neurons gain mutations at similar yearly rates across six species, leaving aged humans with uniquely high mutational burdens and transcriptomic dysregulation.
bioRxiv : the preprint server for biology · Caglayan E et al.
Progressive behavioral and cognitive decline in Drosophila harboring AD- associated APOE4 variants
Model organismsPreprintbioRxiv : the preprint server for biology
The microbiota-proteostasis axis: implications in neurodegenerative diseases
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
Cellular and systemic modifiers of alpha-synuclein proteostasis
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
Proteostasis (in)action: the role of co-pathologies in neurodegenerative disease
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
Differential proteostasis imbalance and the molecular basis of distinct synucleinopathies and tauopathies
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
From aggregate structure to disease trajectory: the role of the proteostasis network
ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences