Muscle
Body system138 papersUBERON 0000383
- Human trial18
- Humans56
- Animals15
- Model organisms1
- Cells7
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Latest
138Early cognitive frailty can reverse in rural older adults
In rural older adults, transition intensity from reversible cognitive frailty was 0.429 toward cognitive impairment alone and 0.291 toward physical…In rural older adults, transition intensity from reversible cognitive frailty was 0.429 toward cognitive impairment alone and 0.291 toward physical frailty, versus 0.224 toward further deterioration.
The effects of chronic beetroot juice supplementation with resistance training on skeletal muscle mitochondrial and redox markers in middle-aged and older adults
Sleep Disturbances and Sarcopenia in Older Adults: Clinical Associations, Potential Mechanisms, and Management Strategies
Changes in skeletal muscle and physical function after cardiac surgery: a prospective study
Treatment-dependent association between sarcopenia and ADL at discharge after osteoporotic vertebral fractures
Calcium overload impairs muscle regeneration by driving sustained NFAT signaling
Inhibiting NFAT restored myoblast differentiation in culture and improved myofiber repair in injured mice.Inhibiting NFAT restored myoblast differentiation in culture and improved myofiber repair in injured mice.
Are we at risk of increasing sarcopenia? Implications for osteoarthritis and osteoporosis
Renal Function, Appendicular Lean Mass, and Bone Stiffness: Indirect Associations Through Fibroblast Growth Factor 21
Aged human muscle secretes an enzyme that impairs stem cell maintenance
Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.
Weaker, Not Just Lighter: Monitoring Strength and Function, Not Lean Mass, During GLP-1 Weight Loss
Higher fitness links to lower cognitive impairment in frail adults
In prefrail and frail adults, top-quartile cardiorespiratory fitness was tied to lower odds of cognitive impairment (OR 0.15) versus the lowest…In prefrail and frail adults, top-quartile cardiorespiratory fitness was tied to lower odds of cognitive impairment (OR 0.15) versus the lowest quartile.
CT biomarkers improve postoperative mortality prediction
Adding automated CT biomarkers to an ICD-based frailty score raised one-year mortality prediction AUROC from 0.75 to 0.79 in 7,638 surgery patients.Adding automated CT biomarkers to an ICD-based frailty score raised one-year mortality prediction AUROC from 0.75 to 0.79 in 7,638 surgery patients.
Paraspinal muscle aging differs in Bolivian foragers and US adults
In a study of 741 adults, the age-related difference in extensor density was 41% smaller in Tsimane men than in Framingham Heart Study men.In a study of 741 adults, the age-related difference in extensor density was 41% smaller in Tsimane men than in Framingham Heart Study men.
Gastrodia elata polysaccharide extends worm lifespan and mitigates age-related deficits in mice
The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in…The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.
Genetically predicted TNF-beta protects against sarcopenia traits in humans
A Mendelian randomization analysis of 91 circulating inflammatory markers identified tumor necrosis factor-beta as causally linked to better muscle…A Mendelian randomization analysis of 91 circulating inflammatory markers identified tumor necrosis factor-beta as causally linked to better muscle mass, grip strength, and walking pace.