Treadmill exercise

1. Treadmill exercise decreases fasting glucose in mice.

   Animalsin diabetic mice5° slope, 12 m/min, 20-50 min/day, 5 days/week8 weeksmales

   Treadmill Exercise is Associated with Intestinal Barrier and Cardiac Nlrp3 Gene Expression Changes in Diabetic Mice · Journal of visualized experiments : JoVE · 25 Sep 2026

Fasting glucose →

1. Treadmill exercise decreases Bax/Bcl-2 mRNA ratio in mice (3.06 ± 0.19 vs. 1.48 ± 0.10, P < 0.001).

   Animalsin diabetic miceheart5° slope, 12 m/min, 20-50 min/day, 5 days/week8 weeksmales

   Treadmill Exercise is Associated with Intestinal Barrier and Cardiac Nlrp3 Gene Expression Changes in Diabetic Mice · Journal of visualized experiments : JoVE · 25 Sep 2026

Bax/Bcl-2 mRNA ratio →

1. Treadmill exercise increases OCLN in mice (0.38 ± 0.04 vs. 0.79 ± 0.05, P < 0.001).

   Animalsin diabetic micecolon5° slope, 12 m/min, 20-50 min/day, 5 days/week8 weeksmales

   Treadmill Exercise is Associated with Intestinal Barrier and Cardiac Nlrp3 Gene Expression Changes in Diabetic Mice · Journal of visualized experiments : JoVE · 25 Sep 2026

OCLN →