Eli Lilly and Company
CompanyUnited States
Eli Lilly and Company develops 18 assets, the furthest approved (donanemab in Alzheimer's disease). Mostly small molecule and peptide acting on Insulin/IGF-1 signalling, GLP1R and lipid and ceramide metabolism; based in the United States.
- Assets
- 18
- Furthest
- Approved
- Trials
- 476
- Signals
- 11
Pipeline
18Monoclonal antibody targeting N3pG-beta-amyloid to promote clearance of amyloid plaques.
ApprovedAntibodyAPPProteostasisAlzheimer's diseaseamyloid pathology
GLP-1 receptor agonist that enhances glucose-dependent insulin secretion.
ApprovedProtein or enzymeInsulin/IGF-1 signallingGLP1Rcardiovascular diseasecardiovascular events
Inhibits renal SGLT2 to reduce glucose reabsorption and lower blood glucose
ApprovedSmall moleculeAMPK signallingAutophagycardiovascular deathcardiovascular disease
15 more assets
Full company profiles: pipeline, trials, funding and people.
See Pro- Evidence behind the mechanisms11
- Trials692
- Signals20
- Integrity notices3
- Similar companies6
Papers
Orforglipron matches insulin glargine on cardiovascular safety
Lancet (London, England)1 Oct 2026
Retatrutide reduces weight and pain in adults with obesity
The New England journal of medicine1 Oct 2026
Retatrutide reduces bodyweight in obesity and type 2 diabetes
Lancet (London, England)30 Sept 2026
Diabetes therapy : research, treatment and education of diabetes and related disorders8 Sept 2026
The lancet. Diabetes & endocrinology21 Aug 2026
Updated 7 Oct 2026 · 296 sources