Kidney disease

Disease7 papers2 findings

  • Humans5

Effects

1

Epigenetic age

upin humans1

1 study
  1. Kidney disease increases epigenetic age in humans.

    Humanskidney

    Kidney tubular epithelial cells drive accelerated epigenetic aging in disease · Nature aging · 24 Sep 2026

Epigenetic age →

Associations

1

Screening

upin humans1+32%

1 study
  1. screening is associated with kidney disease in humans (31.7%).

    Humansin participants screened at HIV clinics and COVID-19 vaccine clinicsOctober 2023 to December 2023n = 461

    Integrating non-communicable disease screening to COVID-19 and human immunodeficiency virus care in Johannesburg South Africa: a pilot model for low- and middle-income countries · Frontiers in public health · 17 Sep 2026

Latest

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Scientific ReportsAnimals

TMEM174 deficiency shortens lifespan and stiffens vessels in mice

Knocking out the proximal tubule protein in mice shortened survival, whereas altering dietary phosphate intake regulated vascular calcification…Knocking out the proximal tubule protein in mice shortened survival, whereas altering dietary phosphate intake regulated vascular calcification, stiffness, and mortality.

medRxivHumansPreprint

NMR metabolomics improves prediction of cardiometabolic diseases

In 54,933 healthcare system participants, profiling 250 NMR biomarkers enhanced standard risk prediction for type 2 diabetes, kidney disease, and…In 54,933 healthcare system participants, profiling 250 NMR biomarkers enhanced standard risk prediction for type 2 diabetes, kidney disease, and liver disease.

Nature MedicineHuman trial

Semaglutide curbs kidney vascular resistance and fibrosis

In 106 people with diabetes and kidney disease, 52 weeks of semaglutide reduced vascular resistance and stabilized markers of fibrosis compared to…In 106 people with diabetes and kidney disease, 52 weeks of semaglutide reduced vascular resistance and stabilized markers of fibrosis compared to placebo.