Premature organelle aging

Biomarker

2 findings

“Individuals with four or more prematurely aged compartments exhibited up to 22-fold higher kidney disease risk and up to 8-fold higher mortality risk.”
Organelle Aging Predicts Human DiseasebioRxiv2026doi:10.64898/2026.11.01.763400

Associations

2

Mortality

upin humans1

1 study
  1. Premature organelle aging is associated with mortality in humans (Four or more prematurely aged compartments) (Up to 8-fold higher mortality risk).

    “Individuals with four or more prematurely aged compartments exhibited up to 22-fold higher kidney disease risk and up to 8-fold higher mortality risk.”

    HumansFour or more prematurely aged compartmentsn = 61,931

    Measures of aging in cell structures linked to disease risk

    bioRxivPreprint

Kidney disease

upin humans1

1 study
  1. Premature organelle aging is associated with kidney disease in humans (Four or more prematurely aged compartments) (Up to 22-fold higher kidney disease risk).

    “Individuals with four or more prematurely aged compartments exhibited up to 22-fold higher kidney disease risk and up to 8-fold higher mortality risk.”

    HumansFour or more prematurely aged compartmentsn = 61,931

    Measures of aging in cell structures linked to disease risk

    bioRxivPreprint

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