Intrinsic capacity score
Biomarker2 papers4 findings
In a human study, higher intrinsic capacity scores correlate with less frailty, less functional impairment and lower epigenetic age; intrinsic capacity scores also predict mortality.
- Humans1
Associations
4Mortality
upin humans1
1 study
Mortality
upin humans1
Intrinsic capacity score predicts mortality in humans (AUC = 0.71-0.74).
Humansn = 30,097
Measuring intrinsic capacity among Canadian adults: a population-based study using the Canadian Longitudinal Study on Aging (CLSA) · Lancet regional health. Americas · 15 Sep 2026
Functional impairment
downin humans1
1 study
Functional impairment
downin humans1
Intrinsic capacity score is associated with functional impairment in humans (r = -0.29).
Humansn = 30,097
Measuring intrinsic capacity among Canadian adults: a population-based study using the Canadian Longitudinal Study on Aging (CLSA) · Lancet regional health. Americas · 15 Sep 2026
Epigenetic age
downin humans1
1 study
Epigenetic age
downin humans1
Intrinsic capacity score is associated with epigenetic age in humans (r = -0.42).
Humansn = 30,097
Measuring intrinsic capacity among Canadian adults: a population-based study using the Canadian Longitudinal Study on Aging (CLSA) · Lancet regional health. Americas · 15 Sep 2026
Frailty
downin humans1
1 study
Frailty
downin humans1
Intrinsic capacity score is associated with frailty in humans (r = -0.36).
Humansn = 30,097
Measuring intrinsic capacity among Canadian adults: a population-based study using the Canadian Longitudinal Study on Aging (CLSA) · Lancet regional health. Americas · 15 Sep 2026