PPAR signalling

Pathway1 paperGO 0035357

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Science Translational MedicineHuman trial

Cranial bone marrow monocytes drive brain injury inflammation and respond to fenofibrate

Targeting PPARα deficiency in cranial bone marrow monocytes improved cognitive function and reduced neurodegeneration markers in older patients with…Targeting PPARα deficiency in cranial bone marrow monocytes improved cognitive function and reduced neurodegeneration markers in older patients with chronic brain injury.