PPARA
Gene2 papersHGNC 9232MGI 104740NCBI Gene 5465Taxon 9606
- Human trial1
- Animals1
Latest
2Science Translational MedicineHuman trial
Cranial bone marrow monocytes drive brain injury inflammation and respond to fenofibrate
Targeting PPARα deficiency in cranial bone marrow monocytes improved cognitive function and reduced neurodegeneration markers in older patients with…Targeting PPARα deficiency in cranial bone marrow monocytes improved cognitive function and reduced neurodegeneration markers in older patients with chronic brain injury.
FASEB JournalAnimals
4-Octyl itaconate restores parotid gland function in aging mice
The itaconate derivative reduces fibrosis and lipid buildup while curbing oxidative stress through AMPK signaling pathways.The itaconate derivative reduces fibrosis and lipid buildup while curbing oxidative stress through AMPK signaling pathways.