PPARG
Gene3 papers2 findingsHGNC 9236MGI 97747NCBI Gene 5468Taxon 9606
- Humans1
- Animals2
Effects
1Inverse fractional anisotropy
downin silico1
1 study
Inverse fractional anisotropy
downin silico1
PPARG decreases inverse fractional anisotropy in silico (β = −0.50, 95% CI −0.99 to −0.02, p = 0.04).
In silicocortex cis-eQTL analyses
Evaluating Diabetes Drug Targets for Vascular Dementia Prevention Using Drug Target Mendelian Randomisation · medRxiv · 29 Sep 2026 · Preprint
Upstream
1RORA
downin mouse cells1
1 study
RORA
downin mouse cells1
RORA decreases PPARG in mouse cells.
Cellsshown by deficiencymacrophages
Myeloid deficiency of RORα exacerbates lipid dysregulation and laser-induced choroidal neovascularization · Angiogenesis · 25 Sep 2026
Latest
3Deleting liver growth hormone receptors accelerates aging phenotypes and shortens lifespan in mice
The loss of hepatic growth hormone signaling disrupts lipid metabolism and causes mitochondrial damage that can be counteracted by inhibiting PDK4.The loss of hepatic growth hormone signaling disrupts lipid metabolism and causes mitochondrial damage that can be counteracted by inhibiting PDK4.