Palmitoylethanolamide
Intervention1 paper3 findingsPubChem 4671ChEBI 71464
- Cells1
Outcomes
3Mitochondrion
downin mouse cells1Very low certainty
1 study
Mitochondrion
downin mouse cells1Very low certainty
Palmitoylethanolamide impairs mitochondrion in mouse cells.
CellsRANKL-induced BMMs
Palmitoylethanolamide alleviates osteoclast activation and reduces bone loss in osteoporosis by regulating mitochondrial function · Bone · 7 Sep 2026
Bone loss
downin mice1Very low certainty
1 study
Bone loss
downin mice1Very low certainty
Palmitoylethanolamide decreases bone loss in mice.
Animalsin ovariectomized mice
Palmitoylethanolamide alleviates osteoclast activation and reduces bone loss in osteoporosis by regulating mitochondrial function · Bone · 7 Sep 2026
Osteoclast differentiation
downin mouse cells1Very low certainty
1 study
Osteoclast differentiation
downin mouse cells1Very low certainty
Palmitoylethanolamide decreases osteoclast differentiation in mouse cells.
CellsRANKL-induced
Palmitoylethanolamide alleviates osteoclast activation and reduces bone loss in osteoporosis by regulating mitochondrial function · Bone · 7 Sep 2026
Trials
10In trials
Phase 4 · Completed · 1 trial
Phase 2 · Results posted · 2 trials
Tourette Syndrome
Phase 2 · Results posted · 2 trials
Phase 2 · Recruiting · 1 trial
Diabetic peripheral neuropathy
Phase 2 · Recruiting · 1 trial
Phase 2 · Completed · 1 trial
All 7Fewer
Phase 2 · Status unknown · 1 trial
Trial sponsors
Company3 trialsPhase 2520 people
Company1 trialPhase 260 people
Clinica Urologica Molinette - Città della Saliute e della Scienza
1 trialPhase 448 people
The Israeli Medical Center for Alzheimer's
1 trialPhase 2100 people
Academic and Community Cancer Research United
1 trialPhase 288 people
Fondazione IRCCS Policlinico San Matteo di Pavia
1 trialPhase 240 people
Rodrigo Machado-Vieira, MD, PhD, MSc
1 trialPhase 234 people
1 trialPhase 217 people