Circadian clock

Animals3
Model organisms1
Cells1
In silico1

Latest

AMPK lengthens the circadian clock period through NAD+-dependent regulation of Bmal1

Experiments in human cells and computational modeling show that fasting sensor AMPK requires NAD+ and PGC-1-alpha to modulate cellular circadian rhythms.

bioRxiv · Vandenberghe A et al.

Paper

AnimalsPeer-reviewed1 Oct

Circadian E3 ligase FBXL21 regulates daily muscle proteostasis by targeting DNAJB6

Loss of FBXL21 disrupts client protein degradation, worsening stress responses in muscle cells and mutant mice.

EMBO reports · Lim JY et al.

Paper

Melatonin and Diabetic Nephropathy: From Mechanistic Pathways to Translational Opportunities in Clinical Management

ReviewCurrent medicinal chemistry1 Oct

Sleep and circadian regulation of DNA repair and retrotransposons in neuronal genome stability and neurodegenerative disease mechanisms

ReviewFrontiers in neuroscience1 Oct

Spaceflight Is Associated with an Age-Conserved Kidney Transcriptomic Signature Linked to Inflammation, Tubular Channelopathy, and Senescence

In silicoPreprintPreprints.org30 Sep

The circadian clock: an important factor modifying the effect of physical activity on the lifespan of Drosophila melanogaster

Model organismsActa neurobiologiae experimentalis30 Sep

Genomic Stress and DNA Repair During Macrophage Differentiation and Inflammatory Activation

ReviewInternational journal of molecular sciences28 Sep

Drosophila melanogaster as a Model for Autism Spectrum Disorder: Insights into Lifelong Neuronal Vulnerability

ReviewInternational journal of molecular sciences28 Sep

Structural Entropy of Liver Histological Sections as an Integrative Index of Tissue Disorganization in Constant-Light-Induced Hepatic Remodeling with Aging-Associated Features

AnimalsBiomedicines26 Sep

Hesperetin Attenuates Experimentally Induced Skeletal Muscle Dysfunction by Modulating Time-of-Day-Dependent Gene Expression and Mitochondrial Redox-Related Markers

AnimalsAntioxidants (Basel, Switzerland)26 Sep