Advances in Gerontology

Chronobiotics as potential geroprotectors

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Abstract

The article analyses the impact of chronobiotics on aging processes and their potential role in geroprotection. Key mechanisms of circadian regulation and their association with age-related diseases, including neurodegenerative and metabolic disorders, are examined. Based on existing scientific data, promising chronobiotics such as melatonin, resveratrol, and their analogs are analysed in terms of their alignment with geroprotector criteria. The main challenges in implementing chronobiotics in clinical practice, including individual chronotypes, genetic factors, and the lack of standardized application protocols, are discussed. In conclusion, promising research directions and recommendations for integrating chronobiotics into healthy aging strategies are proposed.

The paper

Syktyvkar State University

Advances in Gerontology, 1 Jan 2025

PubMed 41172309