Vutiglabridin
- 1 lab in 1 country
- Funders: Daegu Gyeongbuk Institute of Science and Technology and 3 more
- 3 of 3 findings with company ties
- Cells1
Outcomes
3Mitochondrial dysfunction
downin human cells1
1 study
Mitochondrial dysfunction
downin human cells1
Vutiglabridin prevents mitochondrial dysfunction in human cells.
“preventing the alterations of mitochondrial function and structure that occur during the process of cellular senescence”
Cellsin senescent primary human dermal fibroblasts
Antioxidants (Basel, Switzerland)16 Jan 2024
Circadian clock
upin human cells1
1 study
Circadian clock
upin human cells1
Vutiglabridin improves circadian clock in human cells.
“alleviates all investigated markers of cellular senescence (SA-β-gal, CDKN1A, CDKN2A) and dysfunctional cellular circadian rhythm (BMAL1)”
Cellsin senescent primary human dermal fibroblasts
Antioxidants (Basel, Switzerland)16 Jan 2024
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Vutiglabridin decreases cellular senescence in human cells.
“chronic treatment of senescent primary human dermal fibroblasts (HDFs) with vutiglabridin alleviates all investigated markers of cellular senescence (SA-β-gal, CDKN1A, CDKN2A)”
Cellsin senescent primary human dermal fibroblasts
Antioxidants (Basel, Switzerland)16 Jan 2024
Latest
Antioxidants
Vutiglabridin Alleviates Cellular Senescence with Metabolic Regulation and Circadian Clock in Human Dermal Fibroblasts
Experiments in human cellsInterventions
Experimental Gerontology
Vutiglabridin exerts anti-ageing effects in aged mice through alleviating age-related metabolic dysfunctions
Experiments in animalsInterventions