Cardiometabolic risk
Biomarker2 papers6 findings
One human study links waist circumference, body mass index and waist-to-height ratio to higher cardiometabolic risk, with waist-to-height ratio also predicting risk. A review links sleep deprivation and the circadian clock to cardiometabolic risk in humans.
- Humans1
Associations
5Waist-to-height ratio
upin humans1OR 2.64
1 study
Waist-to-height ratio
upin humans1OR 2.64
Waist-to-height ratio predicts cardiometabolic risk in humans (AUC 0.780).
Humansn = 2,412
Comparative Discriminatory Ability of Body Mass Index, Percent Body Fat, Waist Circumference, and Waist-to-Height Ratio for Cardiometabolic Risk Among Korean Adults: A Cross-Sectional Study Using the Korea National Health and Nutrition Examination Survey (KNHANES) 2024 · Biological research for nursing · 7 Sep 2026
Waist-to-height ratio raises the risk of cardiometabolic risk in humans (OR 2.64, 95% CI 2.32-3.00).
Humansadjusted for age and sexn = 2,412
Comparative Discriminatory Ability of Body Mass Index, Percent Body Fat, Waist Circumference, and Waist-to-Height Ratio for Cardiometabolic Risk Among Korean Adults: A Cross-Sectional Study Using the Korea National Health and Nutrition Examination Survey (KNHANES) 2024 · Biological research for nursing · 7 Sep 2026
Circadian clock
upin humans1
1 study
Circadian clock
upin humans1
Circadian clock is associated with cardiometabolic risk in humans.
Review
[Sleep alterations as a risk factor for cardiometabolic health: emerging evidence and clinical implications] · Giornale italiano di cardiologia (2006) · 26 Sep 2026
Sleep deprivation
upin humans1
1 study
Sleep deprivation
upin humans1
Sleep deprivation is associated with cardiometabolic risk in humans.
Review
[Sleep alterations as a risk factor for cardiometabolic health: emerging evidence and clinical implications] · Giornale italiano di cardiologia (2006) · 26 Sep 2026
Body mass index
upin humans1OR 2.4
1 study
Body mass index
upin humans1OR 2.4
Body mass index raises the risk of cardiometabolic risk in humans (OR 2.40, 95% CI 2.12-2.72).
Humansadjusted for age and sexn = 2,412
Comparative Discriminatory Ability of Body Mass Index, Percent Body Fat, Waist Circumference, and Waist-to-Height Ratio for Cardiometabolic Risk Among Korean Adults: A Cross-Sectional Study Using the Korea National Health and Nutrition Examination Survey (KNHANES) 2024 · Biological research for nursing · 7 Sep 2026
Waist circumference
upin humans1OR 2.84
1 study
Waist circumference
upin humans1OR 2.84
Waist circumference raises the risk of cardiometabolic risk in humans (OR 2.84, 95% CI 2.46-3.28).
Humansadjusted for age and sexn = 2,412
Comparative Discriminatory Ability of Body Mass Index, Percent Body Fat, Waist Circumference, and Waist-to-Height Ratio for Cardiometabolic Risk Among Korean Adults: A Cross-Sectional Study Using the Korea National Health and Nutrition Examination Survey (KNHANES) 2024 · Biological research for nursing · 7 Sep 2026
Funding
National Heart, Lung, and Blood InstituteUS$5.5mNational Institute of Diabetes and Digestive and Kidney DiseasesUS$3.4mNational Institute of Environmental Health SciencesUS$921.2k19 grants since 2001
National Heart, Lung, and Blood InstituteUniversity of UtahUS$752.7k2025–2030
National Heart, Lung, and Blood InstituteEmory UniversityUS$162k2024–2028
(CIRCADIAN) Circadian Disruption as Mediator of Cardiometabolic Risk in Air Pollution
National Institute of Environmental Health SciencesCase Western Reserve UniversityUS$921.2k2021–2029
National Cancer InstituteSloan-kettering Inst Can ResearchUS$731.8k2024–2029
National Institute of Diabetes and Digestive and Kidney DiseasesUniversity of PennsylvaniaUS$1m2026–2031
Genomic Architecture of Lifecourse Patterns of Adiposity Change and Cardiometabolic Risk
National Institute of Diabetes and Digestive and Kidney DiseasesGeisinger ClinicUS$857.7k2020–2030
National Institute of Diabetes and Digestive and Kidney DiseasesYale UniversityUS$724.5k2023–2028
Quantifying cardiometabolic risks by AI based assay of photoplethysmogram data
National Heart, Lung, and Blood InstituteEast Carolina UniversityUS$561.1k2026–2029
Discerning the molecular mediators between cardiometabolic risk factors and Alzheimer's disease
National Institute on AgingStanford UniversityUS$125.8k2026–2030
National Heart, Lung, and Blood InstituteIcahn School of Medicine at Mount SinaiUS$853.3k2026–2031
Latest
279Vascular cognitive impairment in China: Epidemiology, risk factors, healthcare system, management challenges, therapeutic modalities, and prevention strategies
Hypothalamic amenorrhea in mid-adulthood linked to heart disease
Mid-adulthood functional hypothalamic amenorrhea was linked to a 62% higher cardiovascular disease risk and an HR of 1.91 for coronary heart disease…Mid-adulthood functional hypothalamic amenorrhea was linked to a 62% higher cardiovascular disease risk and an HR of 1.91 for coronary heart disease compared to regular cycles.
Cardiometabolic burden is linked to CVD and death in MASLD
In 72,922 adults with MASLD, each extra risk factor carried a hazard ratio of 1.17 for incident CVD and 1.09 for direct death.In 72,922 adults with MASLD, each extra risk factor carried a hazard ratio of 1.17 for incident CVD and 1.09 for direct death.
Effects of corn-derived dietary fibers on cardiometabolic risk factors: a systematic review and meta-analysis of randomized controlled trials
Depressive symptom profiles and risk of cardiometabolic disease incidence
Body fat and inflammation link ultraprocessed food to heart risk
In 6,531 adults, waist-to-height ratio mediated 44% and interleukin-6 mediated 13% of the association between ultraprocessed food intake and incident…In 6,531 adults, waist-to-height ratio mediated 44% and interleukin-6 mediated 13% of the association between ultraprocessed food intake and incident cardiovascular disease.