Grip strength
Biomarker1 paper
- Humans1
Latest
6Genetically predicted TNF-beta protects against sarcopenia traits in humans
A Mendelian randomization analysis of 91 circulating inflammatory markers identified tumor necrosis factor-beta as causally linked to better muscle mass, grip strength, and walking pace.
Inhibiting miR-128-3p restores muscle mass and function in aged mice
The microRNA inhibitor also improved cardiac outcomes after infarction and reduced pathology in mouse and pig models of muscular dystrophy.
Proteomic organ clocks predict mortality but trail established physiological and epigenetic biomarkers
In an older Scottish cohort, epigenetic age and brain volume outmatched plasma proteomic organ clocks for predicting long-term all-cause mortality.
Engineered cardiac transcription factor restores vision and reduces frailty in aging mice
A genome-scale screen in retinal cells identified NKX2-5 variants that conferred oxidative resilience and improved physical function without detectable toxicity.
Encapsulated sustained-release whey protein improves muscle mass and strength in sarcopenic mice
A specialized encapsulation system slows protein digestion to boost muscle signaling and physical endurance in a murine sarcopenia model.