Lung cancer
Disease3 papers2 findings
- Humans1
- Animals1
Interventions
1Rapamycin + doxorubicin
downin mice1
1 study
Rapamycin + doxorubicin
downin mice1
Rapamycin + doxorubicin decreases lung cancer in mice.
Animalschemoresistant lung cancer modelL1CAM aptamer-modified DPPC nanoliposomeslung
Inhalable nanoliposomes target senescence and overcome chemoresistance in mouse lung cancer · Biomaterials · 23 Sep 2026
Associations
1ASXL1 mutation
upin humans1
1 study
ASXL1 mutation
upin humans1
ASXL1 mutation raises the risk of lung cancer in humans (hazard ratio = 3.2).
Humanshigh variant allele fraction (high-VAF), adjusted for age, sex, BMI, smoking status, and genetic ancestry
Clonal blood mutations in ASXL1 associate with higher lung cancer risk · Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 28 Sep 2026
Latest
3Mosaic Loss of the Y Chromosome: Mechanisms and Diseases
Inhalable nanoliposomes target senescence and overcome chemoresistance in mouse lung cancer
The formulation co-delivers rapamycin and doxorubicin across the mucus barrier to inhibit mTOR and suppress tumor growth without evident systemic toxicity.
Biomaterials · Man Y et al.
Clonal blood mutations in ASXL1 associate with higher lung cancer risk
Researchers analyzing two large human cohorts found that ASXL1-mutant clonal hematopoiesis linked to more than triple the risk of lung cancer in smokers.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · Zhang Z et al.