Neutrophil-to-lymphocyte ratio
Biomarker5 papers3 findings
- Humans5
Interventions
1GLP-1 receptor agonists
downin humans1
1 study
GLP-1 receptor agonists
downin humans1
GLP-1 receptor agonists decrease neutrophil-to-lymphocyte ratio in humans (mean difference of -0.67 [95% CI, -0.89 to -0.45]).
“lower neutrophil-to-lymphocyte ratio (3.97 vs 4.64, with a mean difference of -0.67 [95% CI, -0.89 to -0.45])”
Humans12 months
Real-world Evidence for Improvements in Inflammation and Anemia Biomarkers After the Initiation of GLP-1RA in Patients Receiving Hemodialysis · Kidney medicine · 17 Jul 2026
Associations
2Cardiovascular mortality
upin humans1HR 1.32
1 study
Cardiovascular mortality
upin humans1HR 1.32
Neutrophil-to-lymphocyte ratio predicts cardiovascular mortality in humans (HR 1.32 (95% CI 1.21-1.44)).
“hazard ratios per 1-SD increase were 1.32 (95% CI 1.21-1.44) for NLR”
Humans11.4 yearsn = 15,141
Limited incremental value of three complete-blood-count inflammatory indices for cardiovascular mortality: a development and external validation study in 30,533 US adults · medRxiv · 2 Oct 2026 · Preprint
Cognitive function
downin humans1
1 study
Cognitive function
downin humans1
Neutrophil-to-lymphocyte ratio predicts cognitive function in humans.
HumansADNI cohortn = 1,190
High neutrophil-to-lymphocyte ratio predicts cognitive decline · Frontiers in aging neuroscience · 16 Sep 2026
Latest
5Association of anxiety, depressive symptoms, and inflammatory indices with cardiometabolic multimorbidity
High neutrophil-to-lymphocyte ratio predicts cognitive decline
During five years of follow-up, 42.55% of older adults with high ratios progressed to mild cognitive impairment or dementia compared with 30.82% with…During five years of follow-up, 42.55% of older adults with high ratios progressed to mild cognitive impairment or dementia compared with 30.82% with normal ratios.